产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗血管内皮生长因子受体1抗体
目录 :
MBS175272
规格 :
0.1毫克
价格 :
245美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
产品信息
目录号 :
MBS175272
产品类型 :
抗体
产品全称 :
抗血管内皮生长因子受体1抗体
产品简称 :
血管内皮生长因子受体1
产品名称同义词 :
Vascular endothelial growth factor receptor 1(VEGFR-1); fms-related tyrosine kinase 1(vascular endothelial growth factor/vascular permeability factor; EC 2.7.10.1 antibody; Flt 1 antibody; FLT antibody; Flt-1 antibody; Flt1 antibody; Fms like tyrosine kinase 1 antibody; Fms related tyrosine kinase 1(vascular endothelial growth factor/vascular permeability factor receptor) antibody; Fms related tyrosine kinase 1 antibody; Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody; Fms-like tyrosine kinase 1 antibody; FRT antibody; Soluble VEGF receptor 1 14 antibody; Soluble VEGFR1 variant 2 antibody; Soluble VEGFR1 variant 21 antibody; Tyrosine protein kinase FRT antibody; Tyrosine protein kinase receptor FLT antibody; Tyrosine-protein kinase FRT antibody; Tyrosine-protein kinase receptor FLT antibody; Vascular endothelial growth factor receptor 1 antibody; Vascular endothelial growth factor receptor 1 Precursor antibody; Vascular endothelial growth factor vascular permeability factor receptor antibody; Vascular permeability factor receptor 1 antibody; Vascular permeability factor receptor antibody; VEGFR 1 antibody; VEGFR-1 antibody; VEGFR1 antibody; VGFR1_HUMAN antibody
其他名称 :
Vascular endothelial growth factor receptor 1; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor 1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); fms-related tyrosine kinase 1; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; FLT; Vascular permeability factor receptor
产品基因名称 :
FLT1
其他基因名称 :
FLT1;FLT1;FLT;FLT-1;VEGFR1;VEGFR-1;FLT;FRT;VEGFR1;VEGFR-1;FLT-1;FLT
UniProt数据库进入名 :
VGFR1_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
序列长度 :
1338
纯度 :
免疫原亲和纯化
形式 :
冻干
储存稳定性 :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
检测过的应用 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human VEGF Receptor 1 (1299-1317aa HVSEGKRRFTYDHAELERK).
其他信息2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
产品描述 :
Description: Rabbit IgG polyclonal antibody for Vascular endothelial growth factor receptor 1(FLT1) detection. Tested with WB in Human. Background: Vascular endothelial growth factor receptor 1(FLT1) is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
NCBI GI登录号 :
143811474
NCBI登录号 :
P17948.2
UniProt数据库登录号 :
P17948
NCBI分子量 :
41,175 Da
NCBI信号通路 :
Angiogenesis Pathway (198772); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Endocytosis Pathway (102279); Endocytosis Pathway (102181); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); Glypican 1 Network Pathway (138010); HIF-1 Signaling Pathway (695200)
NCBI总结 :
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
UniProt数据库总结 :
VEGFR1: a receptor tyrosine kinase of the VEGFR family. Receptor for VEGF, VEGFB and PGF. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Two splice variant isoforms have been described. Isoform SFlt1 may have an inhibitory role in angiogenesis. Protein type: Membrane protein, integral; Protein kinase, tyrosine (receptor); Kinase, protein; Protein kinase, TK; EC 2.7.10.1; TK group; VEGFR family. Chromosomal Location of Human Ortholog: 13q12. Cellular Component: extracellular space; focal adhesion; integral to plasma membrane; plasma membrane; receptor complex; endosome. Molecular Function: identical protein binding; vascular endothelial growth factor receptor activity; protein binding; growth factor binding; transmembrane receptor protein tyrosine kinase activity; ATP binding. Biological Process: cell migration; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; patterning of blood vessels; monocyte chemotaxis; positive regulation of MAP kinase activity; positive regulation of angiogenesis; positive regulation of MAPKKK cascade; positive regulation of cell proliferation; blood vessel morphogenesis; sprouting angiogenesis; embryonic morphogenesis; vascular endothelial growth factor receptor signaling pathway; cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration
尺寸1 :
0.1毫克
价格1 :
245美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。