抗体

抗激肽释放酶1抗体

MBS175345

0.1毫克

245美元

多克隆

兔

未共轭

免疫印迹, 免疫组化-石蜡切片

抗体

抗激肽释放酶1抗体

激肽释放酶1

Kallikrein-1; kallikrein 1; Glandular kallikrein 1 antibody; hK 1 antibody; hK1 antibody; Kallikrein serine protease 1 antibody; Kallikrein-1 antibody; Kidney/pancreas/salivary gland kallikrein antibody; Klk 6 antibody; KLK1 antibody; KLK1_HUMAN antibody; Klk6 antibody; KLKR antibody; Tissue kallikrein antibody

Kallikrein-1; Kallikrein-1; kallikrein-1; KAL-B; kallikrein 6; renal kallikrein; tissue kallikrein-6; true tissue kallikrein; glandular kallikrein K1; kallikrein renal/pancreas/salivary; kallikrein 1; Glandular kallikrein K1; KAL-B; Renal kallikrein; Tissue kallikrein-6; mGK-6

KLK1

Klk1; Klk1; Kal; Klk6; mGk-6; Klk1b6; 0610007D04Rik; Klk-6; Klk6; mGK-6

KLK1_MOUSE

多克隆

IgG

兔

小鼠

261

No cross reactivity with other proteins.

免疫原亲和纯化

冻干

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

免疫印迹(免疫印迹), 免疫组化石蜡(免疫组化-P)

WB: . Concentration:0.1-0.5ug/ml. Tested Species: Ms. IHC-P: . Concentration: 0.5-1ug/ml. Tested Species: MS. Antigen Retrieval: By Heat. Tested Species: In-house tested species with positive results. Predicted Species: Species to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 1 (243-261aa YTRVLNFNTWIRETMAEND).

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for Kallikrein-1(KLK1) detection. Tested with WB, IHC-P in Mouse. Background: KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

17433705

P15947.3

P15947

28,775 Da

Activation Of Matrix Metalloproteinases Pathway (1001029); Degradation Of The Extracellular Matrix Pathway (1001028); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213309); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276); Extracellular Matrix Organization Pathway (1001015); Metabolism Of Proteins Pathway (970583); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (1000422)

KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.21.35; Protease. Cellular Component: nucleus. Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity. Biological Process: proteolysis

0.1毫克

245美元