产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗胶原IV抗体
目录 :
MBS175589
规格 :
0.1毫克
价格 :
245美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
目录号 :
MBS175589
产品类型 :
抗体
产品全称 :
抗胶原IV抗体
产品简称 :
胶原IV
产品名称同义词 :
Collagen alpha-2(IV) chain; collagen, type IV, alpha 2; Arresten antibody; Canstatin antibody; CO4A1_HUMAN antibody; COL4A1 antibody; COL4A1 NC1 domain antibody; COL4A2 antibody; COL4A3 antibody; COL4A4 antibody; COL4A5 antibody; Collagen Alpha 1(IV) Chain antibody; Collagen Alpha 2(IV) Chain antibody; collagen alpha-1(IV) chain antibody; Collagen IV Alpha 1 Polypeptide antibody; Collagen IV Alpha 2 Polypeptide antibody; Collagen Of Basement Membrane Alpha 1 Chain antibody; Collagen Of Basement Membrane Alpha 2 Chain antibody; Collagen Type IV Alpha 1 antibody; Collagen Type IV Alpha 2 antibody; Collagen Type IV Alpha 3 antibody; Collagen Type IV Alpha 4 antibody; Collagen Type IV Alpha 5 antibody; DKFZp686I14213 antibody; FLJ22259 antibody
其他名称 :
Collagen alpha-2(IV) chain; Collagen alpha-2(IV) chain; collagen alpha-2(IV) chain; collagen alpha-2(IV) chain; canstatin; collagen, type IV, alpha 2
产品基因名称 :
COL4A2
其他基因名称 :
COL4A2;COL4A2;ICH;POREN2
UniProt数据库进入名 :
CO4A2_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
1712
纯度 :
免疫原亲和纯化
形式 :
冻干
储存稳定性 :
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化)石蜡, 免疫组化(免疫组化)福尔马林, 免疫细胞化学免疫细胞化学
其它信息1 :
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen IV (1697-1712aa LIRTHISRCQVCMKNL), identical to the related rat and mouse sequences.
其他信息2 :
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
产品描述 :
Description: Rabbit IgG polyclonal antibody for Collagen alpha-2(IV) chain(COL4A2) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat. Background: Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
NCBI GI登录号 :
143811377
NCBI登录号 :
P08572.4
UniProt数据库登录号 :
P08572
NCBI分子量 :
167,553 Da
NCBI信号通路 :
Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Axon Guidance Pathway 105688!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Collagen Biosynthesis And Modifying Enzymes Pathway 645289!!Collagen Formation Pathway 645288!!Developmental Biology Pathway 477129!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479
NCBI总结 :
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008]
规格 :
0.1毫克
价格 :
245美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。