抗体

Anti-Midkine antibody

MBS175724

0.1毫克

245美元

多克隆

兔

nonconjugated

人类, 小鼠, 大鼠

抗体

Anti-Midkine antibody

Midkine

Midkine(MK); midkine(neurite growth-promoting factor 2); Amphiregulin associated protein antibody; Amphiregulin-associated protein antibody; ARAP antibody; FLJ27379 antibody; MDK antibody; Midgestation and kidney protein antibody; Midkine antibody; MK 1 antibody; MK antibody; MK_HUMAN antibody; MK1 antibody; NEGF 2 antibody; NEGF2 antibody; neurite growth promoting factor 2 antibody; Neurite outgrowth promoting protein antibody; Neurite outgrowth-promoting factor 2 antibody; Neurite outgrowth-promoting protein antibody; Retinoic acid inducible factor antibody

Midkine; Midkine; midkine; retinoic acid inducible factor; amphiregulin-associated protein; midgestation and kidney protein; neurite outgrowth-promoting factor 2; midkine (neurite growth-promoting factor 2); Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein

MDK

MDK;MDK;MK;ARAP;NEGF2;MK1;NEGF2;MK;ARAP

MK_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

143

免疫原亲和纯化

冻干

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

免疫印迹(免疫印迹)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Midkine (108-121aa KKARYNAQCQETIR), identical to the related rat and mouse sequences.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Description: Rabbit IgG polyclonal antibody for Midkine(MDK) detection. Tested with WB in Human, Mouse, Rat. Background: Midkine(MK or MDK) also known as neurite growth-promoting factor 2(NEGF2) is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin(NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. MK is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta(PTP zeta), low density lipoprotein receptor-related protein(LRP1), anaplastic leukemia kinase(ALK) and syndecans is considered to be its receptor

127116

P21741.1

P21741

9,512 Da

Glypican 2 Network Pathway 138035!!NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway 771602!!Signal Transduction Pathway 477114!!Signaling By NOTCH Pathway 106485!!Signaling By NOTCH2 Pathway 576272!!Syndecan-4-mediated Signaling Events Pathway 138064

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

0.1毫克

245美元