产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
Human TLR2 PicoKine ELISA Kit
目录 :
MBS175946
规格 :
96 Wells
价格 :
455美元
更多信息或购买 :
产品信息
目录号 :
MBS175946
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
Human TLR2 PicoKine ELISA Kit
产品简称 :
Toll样受体2
产品名称同义词 :
Toll-like receptor 2; toll-like receptor 2; CD_antigen; CD282; TIL4; Toll like receptor 2; Toll/interleukin 1 receptor like protein 4
其他名称 :
Toll-like receptor; toll-like receptor 2; toll/interleukin 1 receptor-like 4; toll/interleukin-1 receptor-like protein 4; toll-like receptor 2
产品基因名称 :
Toll样受体2
其他基因名称 :
Toll样受体2;TIL4;CD282
UniProt数据库进入名 :
B3KWR9_HUMAN
反应物种 :
人类
序列长度 :
784
特异性 :
Natural and recombinant human TLR2
储存稳定性 :
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
其它信息1 :
Samples: Cell culture supernates, serum and plasma (heparin, EDTA). Assay Type: Sandwich. Detection Range: 156pg/ml-10,000pg/ml. Sensitivity: < 10pg/ml
其他信息2 :
Intra-assay Precision: Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Inter-assay Precision: Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
产品描述 :
Principle of the assay: human TLR2 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for TLR2 has been precoated onto 96-well plates. Standards(NSO, E21-L590) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for TLR2 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human TLR2 amount of sample captured in plate. Background: Toll-like receptor 2 also known as TLR-2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282 (cluster of differentiation 282). TLR-2 plays a role in the immune system. TLR-2 is a membrane protein, a receptor, which is expressed on the surface of certain cells and recognizes foreign substances and passes on appropriate signals to the cells of the immune system. TLR2 expresses as 4- and 4.4-kb mRNAs in heart, brain, and muscle.
UniProt数据库登录号 :
B3KWR9
NCBI分子量 :
89,826 Da
NCBI信号通路 :
Activated TLR4 Signalling Pathway (106400); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Beta Defensins Pathway (530759); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Defensins Pathway (530757); Hepatitis B Pathway (694606); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865)
NCBI总结 :
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]
尺寸1 :
96 Wells
价格1 :
455美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。