产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
DNA连接酶I单克隆抗体
目录 :
MBS190122
规格 :
0.1毫升
价格 :
420美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
产品信息
目录号 :
MBS190122
产品类型 :
抗体
产品全称 :
DNA连接酶I单克隆抗体
产品简称 :
DNA连接酶I
产品名称同义词 :
抗DNA连接酶I;DNA连接酶I
其他名称 :
DNA ligase I; DNA ligase 1; DNA ligase 1; polydeoxyribonucleotide synthase ATP 1; polydeoxyribonucleotide synthase [ATP] 1; ligase I, DNA, ATP-dependent; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1
其他基因名称 :
LIG1;LIG1;MGC117397;MGC130025
UniProt数据库进入名 :
DNLI1_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1 kappa
宿主 :
小鼠
序列长度 :
919
特异性 :
Anti-DNA Ligase I [Murine MAb recognizes human DNA Ligase I, a 125 kD ligase involved in joining of DNA strand breaks.]. This antibody recognizes human DNA Ligase I (125 kD), one of the four ligase proteins found in mammalian cells that are required for the joining of DNA strand breaks that occur during DNA replication, repair, and recombination.
形式 :
100微克蛋白质G纯化抗体在PBS, pH值7.4
储存稳定性 :
This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.
检测过的应用 :
免疫印迹 , 免疫沉淀
应用笔记 :
Immunoblotting: use at 1-5 ug/ml. Immunoprecipitation: use at 1-5 ug/ml. Positive controls: MCF-7 cells or recombinant protein.
其它信息1 :
Antigen: Recombinant human DNA Ligase I (aa 1-919) purified from baculovirus infected Sf9 cells.
其他信息2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
产品种类 :
Cancer Research Products
NCBI GI登录号 :
187143
NCBI登录号 :
AAA59518.1
UniProt数据库登录号 :
P18858
NCBI分子量 :
101,736 Da
NCBI信号通路 :
Base Excision Repair Pathway 105838!!Base Excision Repair Pathway 83043!!Base Excision Repair Pathway 451!!Cell Cycle, Mitotic Pathway 105765!!Chromosome Maintenance Pathway 161048!!DNA Repair Pathway 105837!!DNA Replication Pathway 105897!!DNA Replication Pathway 83039!!DNA Replication Pathway 444!!DNA Strand Elongation Pathway 105789
NCBI总结 :
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq]
UniProt数据库总结 :
Function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Catalytic activity: ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). Cofactor: Magnesium. Ref.18. Subcellular location: Nucleus. Sequence similarities: Belongs to the ATP-dependent DNA ligase family.
规格 :
0.1毫升
价格 :
420美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。