产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
血红素氧化酶单克隆抗体
目录 :
MBS190201
规格 :
0.1毫克
价格 :
470美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
GTS-1
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化
更多信息或购买 :
产品信息
目录号 :
MBS190201
产品类型 :
抗体
产品全称 :
血红素氧化酶单克隆抗体
产品简称 :
血红素氧化酶
产品名称同义词 :
血红素氧化酶
其他名称 :
heme oxygenase-1; Heme oxygenase 1; heme oxygenase 1; OTTHUMP00000198812; heat shock protein, 32-kD; heme oxygenase (decycling) 1
其他基因名称 :
HMOX1;HMOX1;HO-1;HSP32;bK286B10;HO;HO1
UniProt数据库进入名 :
HMOX1_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
GTS-1
宿主 :
小鼠
序列长度 :
288
特异性 :
Heme Oxygenase-1 [Mouse monoclonal antibody to Heme Oxygenase-1]. This antibody reacts with human, rat and mouse heme oxygenase 1. It does not react with rabbit heme oxygenase I or heme oxygenase 2. This antibody will inhibit the activity of human or rat heme oxygenase 1.
形式 :
100微克IgG在10 mM PBS, pH值7.4, 冻干
储存稳定性 :
Lyophilized antibody is stable at 4 degree C for 2 years. Store the reconstituted solution in aliquots at -20 degree C or at 4 degree C for 6 months after the addition of 0.1% sodium azide by the user.
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, 免疫组化
应用笔记 :
ELISA: 1:10,000 dilution with solid phase antigen. Western Blot: 5-10 ug/ml. Immunohistochemistry: 5-10 ug/ml (for use on human frozen or paraffin embedded tissue). Heme oxygenase 1 activity assays.
其它信息1 :
Antigen: Rat heme oxygenase 1.
其他信息2 :
Stabilizer: 1% BSA. Preservatives: None. Dilutions Instructions: Reconstitute in distilled water to the final desired concentration.
产品种类 :
酶和酶抑制剂抗体
NCBI GI登录号 :
579973
NCBI登录号 :
CAA32886.1
UniProt数据库登录号 :
P09601
NCBI分子量 :
32,819 Da
NCBI信号通路 :
HIF-1-alpha Transcription Factor Network Pathway 138045!!Heme Degradation Pathway 160971!!Iron Uptake And Transport Pathway 187191!!Keap1-Nrf2 Pathway 198777!!Metabolism Of Porphyrins Pathway 106325!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Oxidative Stress Pathway 198916!!Porphyrin And Chlorophyll Metabolism Pathway 83021!!Porphyrin And Chlorophyll Metabolism Pathway 407
NCBI总结 :
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq]
UniProt数据库总结 :
Function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Catalytic activity: Heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O. Subcellular location: Microsome. Endoplasmic reticulum. Induction: Heme oxygenase 1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. Sequence similarities: Belongs to the heme oxygenase family.
规格 :
0.1毫克
价格 :
470美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。