产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
人类转铁蛋白单克隆抗体
目录 :
MBS190265
规格 :
0.5毫克
价格 :
300美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类
应用 :
酶联免疫吸附测定
更多信息或购买 :
产品信息
目录号 :
MBS190265
产品类型 :
抗体
产品全称 :
人类转铁蛋白单克隆抗体
产品简称 :
转铁蛋白
产品名称同义词 :
抗转铁蛋白;转铁蛋白
其他名称 :
transferrin; Serotransferrin; serotransferrin; siderophilin; OTTHUMP00000197155; beta-1 metal-binding globulin; transferrin; Beta-1 metal-binding globulin; Siderophilin
其他基因名称 :
TF;TF;PRO1557;PRO2086;DKFZp781D0156
UniProt数据库进入名 :
TRFE_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
宿主 :
小鼠
序列长度 :
698
特异性 :
Anti-Transferrin [N-terminus of human transferrin]. Reacts with the N-terminal domain of human transferrin, Kd = 2.85 x 10^-11 M. This antibody does not cross-react with mouse, rabbit, or bovine transferrin, nor with human lactoferrin.
形式 :
500微克蛋白质A纯化抗体在PBS, pH值7.4
储存稳定性 :
These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles
检测过的应用 :
ELISA, Immunoassay, Immunoflourescence
其它信息1 :
Antigen: Purified human transferrin from pooled human plasma.
其他信息2 :
Stabilizer: None. Preservatives: 0.1% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
产品种类 :
激素和血清蛋白抗体
NCBI GI登录号 :
248648
NCBI登录号 :
AAB22049.1
UniProt数据库登录号 :
P02787
NCBI分子量 :
77,064 Da
NCBI信号通路 :
EPHB Forward Signaling Pathway (138047); Formation Of Platelet Plug Pathway (106029); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation Pathway (106034); Platelet Degranulation Pathway (106050); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048)
NCBI总结 :
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq]
UniProt数据库总结 :
TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: extracellular space; recycling endosome; cell surface; endocytic vesicle; perinuclear region of cytoplasm; early endosome; cytoplasmic membrane-bound vesicle; late endosome; apical plasma membrane; basal plasma membrane; extracellular region; coated pit; endosome membrane; vesicle. Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding. Biological Process: retinal homeostasis; platelet activation; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport. Disease: Atransferrinemia
尺寸1 :
0.5毫克
价格1 :
300美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。