抗体

C/EBP乙抗体(克隆47A1)

MBS200024

0.05毫升

240美元

单克隆

小鼠

未共轭

47A1

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

C/EBP乙抗体(克隆47A1)

C/EBP乙

CEBPB(CCAAT/enhancer binding protein; beta); LAP; CRP2; TCF5; IL6DBP; NF-IL6; MGC32080; C/EBP-beta; CCAAT/enhancer binding protein (C/EBP) beta; NFIL6; liver-enriched transcriptional activator protein; nuclear factor of interleukin 6; interleukin 6-dependent DNA-binding protein

CCAAT/enhancer-binding protein beta isoform a; CCAAT/enhancer-binding protein beta; CCAAT/enhancer-binding protein beta; interleukin 6-dependent DNA-binding protein; nuclear factor NF-IL6; nuclear factor of interleukin 6; transcription factor 5; CCAAT/enhancer binding protein (C/EBP), beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5

C/EBP乙

CEBPB;CEBPB;TCF5;IL6DBP;NF-白细胞介素-6;C/EBP乙;TCF5;C/EBP乙;LAP;唇;TCF-5

CEBPB_HUMAN

单克隆

IgG1, k

47A1

小鼠

人类, 小鼠

345

By protein-G affinity chromatography

液体。 用品在磷酸盐缓冲液(pH值7.4)含0.1％叠氮化钠

1毫克/毫升

Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

ELISA (EIA), Western Blot (WB) (Cell lysate)

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.

Antigen Species: Human. Clone: Anti-human C/EBP beta mAb, clone 47A1, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human C/EBP beta protein. Immunogen: Recombinant human C/EBP-beta (1-271 aa) purified from E Coli

信号转导

CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPalpha, C/EBPbeta, C/EBPdelta, C/EBPepsilon, and C/EBPgamma. Among these proteins, C/EBPbeta is usually highly expressed in liver, intestine, lung and adipose. C/EBPbeta has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated.

Lekstrom-Himes J. et al. (1998) J Biol. Chem. 273, 28545-28548 Parkin SE. et al. (2002) J Biol. Chem; 277, 23563-23572 Su WC. et al. (2003) J Biol. Chem. 278, 51150-51158

28872796

NP_005185

NM_005194.3

15,938 Da

Adipogenesis Pathway 198832!!C-MYB Transcription Factor Network Pathway 138073!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Developmental Biology Pathway 477129!!Diurnally Regulated Genes With Circadian Orthologs Pathway 198813!!EGFR1 Signaling Pathway 198782!!FOXA1 Transcription Factor Network Pathway 137979!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!IFN-gamma Pathway 138040

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013]

0.05毫升

240美元