产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
BMP7抗体(克隆4E7)
目录 :
MBS200028
规格 :
0.05毫升
价格 :
240美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4.00E+07
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS200028
产品类型 :
抗体
产品全称 :
BMP7抗体(克隆4E7)
产品简称 :
BMP7
产品名称同义词 :
Osteogenic protein1; OP-1; Bone morphogenetic protein 7 BMP 7; Eptotermin alfa; OP 1; OP1.
其他名称 :
bone morphogenetic protein 7; Bone morphogenetic protein 7; bone morphogenetic protein 7; osteogenic protein 1; bone morphogenetic protein 7; Osteogenic protein 1; OP-1; INN: Eptotermin alfa
产品基因名称 :
BMP7
其他基因名称 :
BMP7;BMP7;OP-1;OP1;BMP-7;OP-1
UniProt数据库进入名 :
BMP7_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1, k
克隆 :
4.00E+07
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
431
纯度 :
By protein-G affinity chromatography
形式 :
液体。 用品在磷酸盐缓冲液(pH值7.4)含0.1％叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
检测过的应用 :
ELISA (EIA), Western Blot (WB) (Cell lysate)
应用笔记 :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
其它信息1 :
Antigen Species: Human. Clone: Anti-human BMP7 mAb, clone 4E7, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human BMP7 protein. Immunogen: Recombinant human BMP7 (293-431aa) purified from E Coli
产品种类 :
激素&细胞因子
产品描述 :
BMP-7 (bone morphogenetic protein-7), also known as OP-1 (osteogenic protein-1), is a member of the transforming growth factorbeta(TGFbeta) superfamily. BMP-7 plays an essential role during ontogeny of the mammalian eye and kidney, also, is expressed in heart, lung, small intestine, limb bud and teeth. In addition, noggin, one of the soluble BMP antagonists, regulated the action of BMPs on mesenchymal precursor cells, partially through a feedback type of inhibition.
产品引用 :
Gregory kE., et al. (2005) J. Biol, Chem. 280, 27970-27980. Sampath Tk., et al. (1990) J. Biol. Chem. 265, 13198-13205 Godin RE., et al. (1998) Development. 125, 3473-3482 Groppe J., et al. (2002) Nature. 420, 636-642
NCBI GI登录号 :
4502427
NCBI登录号 :
NP_001710
NCBI基因登录号 :
NM_001719.2
NCBI分子量 :
49,313 Da
NCBI信号通路 :
ALK2 Signaling Events Pathway 137983!!BMP Receptor Signaling Pathway 137948!!BMP Signaling Pathway 1084755!!BMP Signaling Pathway 1108218!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Elastic Fibre Formation Pathway 730310!!Endochondral Ossification Pathway 198812!!Extracellular Matrix Organization Pathway 576262!!Hippo Signaling Pathway 749777
NCBI总结 :
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
规格 :
0.05毫升
价格 :
240美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。