抗体

单克隆抗体结缔组织生长因子(CTGF)

MBS2001321

0.01毫克

95美元

单克隆

小鼠

未共轭

[4-2#]

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗体

单克隆抗体结缔组织生长因子(CTGF)

[结缔组织生长因子(CTGF)]

[connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8]

[CTGF]

[CTGF;CTGF;CCN2;NOV2;HCS24;IGFBP8;CCN2;HCS24;IGFBP8;IBP-8;IGF结合蛋白8;IGFBP-8]

单克隆

IgG2b Kappa

[4-2#]

小鼠

人类

The antibody is a Mouse monoclonal antibody raised against CTGF. It has been selected for its ability to recognize CTGF in immunohistochemical staining and western blotting.

蛋白质A/G亲和色谱

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

500µg/毫升

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

免疫印迹;免疫组化;免疫细胞化学;免疫沉淀

Western blotting: 0.5-5µg/mL. Immunohistochemistry: 5-30µg/mL. Immunocytochemistry: 5-30µg/mL. Optimal working dilutions must be determined by end user

免疫印迹(免疫印迹)

Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CTGF (Leu80~Leu200) expressed in E.coli

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2034969

4503123

NP_001892.1

NM_001901.2

P29279

35,205 Da

Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); TGF-beta Receptor Signaling Pathway (138024)

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]

CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q23.2. Cellular Component: cell cortex; cis-Golgi network; cytosol; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bound organelle; perinuclear region of cytoplasm; plasma membrane; proteinaceous extracellular matrix. Molecular Function: fibronectin binding; growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein binding; protein C-terminus binding. Biological Process: aging; angiogenesis; cartilage condensation; cell adhesion; cell differentiation; cell migration; cell-cell signaling; cell-matrix adhesion; epidermis development; fibroblast growth factor receptor signaling pathway; integrin-mediated signaling pathway; lung development; ossification; positive regulation of cell activation; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of JNK cascade; positive regulation of stress fiber formation; regulation of cell growth; regulation of chondrocyte differentiation; regulation of lipid metabolic process; response to amino acid; response to anoxia; response to estradiol; response to glucose stimulus; response to mineralocorticoid stimulus; response to peptide hormone; response to wounding; tissue homeostasis; transcription initiation from RNA polymerase II promoter

0.01毫克

95美元

0.02毫克

105

0.05毫克

130

0.1毫克

160

0.2毫克

200

1毫克

440