产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
LTA抗体(AT15A3)
目录 :
MBS200189
规格 :
0.05毫升
价格 :
240美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT15A3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS200189
产品类型 :
抗体
产品全称 :
LTA抗体(AT15A3)
产品简称 :
LTA
产品名称同义词 :
CLTalpha; Coley's toxin; DIF; Differentiation inducing factor; Hemorrhagic factor; LT; LT alpha; LTA; LTalpha; Lymphotoxin alpha; Lymphotoxin alpha (TNF superfamily; member 1); Natural killer cytotoxic factor; Necrosin; NKCF; OTTHuMP00000037612; OTTHuMP00000037613; TNF B; TNF superfamily member 1; TNFB; TNFbeta; TNFSF 1; TNFSF1; Tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; Tumor necrosis factor superfamily member 1; Lymphotoxin alpha
其他名称 :
lymphotoxin-alpha; Lymphotoxin-alpha; lymphotoxin-alpha; LT-alpha; TNF superfamily, member 1; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1
产品基因名称 :
LTA
其他基因名称 :
LTA;LTA;LT;TNFB;TNFSF1;TNFB;TNFSF1;LT甲
UniProt数据库进入名 :
TNFB_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG2b, k
克隆 :
AT15A3
宿主 :
小鼠
反应物种 :
人类, 小鼠
序列长度 :
205
纯度 :
By protein-G affinity chromatography
形式 :
液体。 用品在磷酸盐缓冲液(pH值7.4)含0.1%叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫荧光(IF)
应用笔记 :
The antibody has been tested by ELISA, Western blot and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:250 ~ 500. Recommended starting dilution is 1:250
其它信息1 :
Antigen Species: Human. Clone: Anti-human LTA mAb, clone AT15A3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human LTA protein. Immunogen: Recombinant human LTA (35-205aa) purified from E.coli
产品种类 :
Cancer
产品描述 :
Lymphotoxin-alpha (LT-alpha; LTA) is member of the TNF ligand superfamily, bind the same TNF receptor and mediate similar pleiotropic effect. LTA, located within the MHC III region of chromosome 6, show close linkage to the HLA class I (HLA-B) and class II (HLA-DR) genes. LTA is proinflammatory cytokine with important biological activity and immunomodulatory function and be known to influence a variety of cellular response. In particular, Polymorphism in the gene encoding LTA appears to contribute to infectious disease susceptibility and infection.
产品引用 :
Ovsyannikova IG, et al. (2010) PLoS One, 5(7):e11806 Boraska V, et al. (2010) BMC Med Genet, 11-69. Sala A, et al. (2010) Pharmacol Rep, 62(3):503-10.
NCBI GI登录号 :
229092381
NCBI登录号 :
NP_001153212
NCBI基因登录号 :
NM_001159740.2
NCBI分子量 :
22,297 Da
NCBI信号通路 :
Apoptosis Pathway 198797!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!IL2 Signaling Events Mediated By STAT5 Pathway 137988!!IL4-mediated Signaling Events Pathway 137933!!NF-kappa B Signaling Pathway 634527
NCBI总结 :
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
规格 :
0.05毫升
价格 :
240美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。