抗体

生物素链接抗体角蛋白18(KRT18)

MBS2002695

0.1毫克

235美元

多克隆

兔

生物素

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗体

生物素链接抗体角蛋白18(KRT18)

[角蛋白18(KRT18)]

[keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18]

[KRT18]

[KRT18;KRT18;K18;CYK18;CYK18;CK-18;K18]

K1C18_HUMAN

多克隆

兔

Antigen-specific Affinity Chromatography.

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

0.45毫克/毫升

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

免疫印迹;免疫组化;免疫细胞化学;免疫沉淀

Western blotting: 0.5-2 ug/mL. Immunohistochemistry: 5-20 ug/mL. Immunocytochemistry: 5-20 ug/mL;. Optimal working dilutions must be determined by end user.

免疫印迹(免疫印迹)

基因敲除验证

Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: Biotin. Traits: Liquid. Immunogen: Recombinant KRT18 (Asp238~Leu396) expressed in E.coli.

Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2003165

生物素抗体

40354195

NP_954657.1

NM_199187.1

P05783

Caspase Cascade In Apoptosis Pathway (137974); EGFR1 Signaling Pathway (198782); Pathogenic Escherichia Coli Infection Pathway (83103); Pathogenic Escherichia Coli Infection Pathway (672459); Pathogenic Escherichia Coli Infection Pathway (516)

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis. Protein type: Cytoskeletal; Nucleolus. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: perinuclear region of cytoplasm; keratin filament; cytoplasm; nucleolus; intermediate filament; microtubule organizing center. Molecular Function: protein binding; structural molecule activity. Biological Process: anatomical structure morphogenesis; viral reproduction; tumor necrosis factor-mediated signaling pathway; intermediate filament cytoskeleton organization and biogenesis; cell cycle; negative regulation of apoptosis; Golgi to plasma membrane CFTR protein transport. Disease: Cirrhosis, Familial

0.1毫克

235美元

0.2毫克

350

1毫克

835