产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
多克隆抗体转铁蛋白受体(TFR)
目录 :
MBS2006760
规格 :
0.01毫克
价格 :
110美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS2006760 图像 1
Western Blot: Sample: Lane1: Human Hela Cells; Lane2: Human Jurkat Cells.
图像 2 :
MyBioSource MBS2006760 图像 2
Western Blot: Sample: Recombinant TFR, Mouse.
图像 3 :
MyBioSource MBS2006760 图像 3
DAB staining on fromalin fixed paraffin-embedded Kidney tissue)
产品信息
目录号 :
MBS2006760
产品类型 :
抗体
产品全称 :
多克隆抗体转铁蛋白受体(TFR)
产品简称 :
[转铁蛋白受体(TFR)]
其他名称 :
[转铁蛋白受体蛋白1;转铁蛋白受体蛋白1;转铁蛋白受体蛋白1;转铁蛋白受体;CD_antigen:CD71]
产品基因名称 :
[TFR]
其他基因名称 :
[Tfrc; Tfrc; TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; 2610028K12Rik; E430033M20Rik; Trfr; TR; TfR; TfR1; Trfr]
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
小鼠
特异性 :
The antibody is a Rabbit polyclonal antibody raised against TFR. It has been selected for its ability to recognize TFR in immunohistochemical staining and western blotting.
纯度 :
Antigen-specific Affinity Chromatography
形式 :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
浓度 :
200微克/毫升
储存稳定性 :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition
检测过的应用 :
免疫印迹;免疫组化;免疫细胞化学;免疫沉淀
应用笔记 :
Western blotting: 0.5-5µg/mL. Immunocytochemistry in formalin fixed cells: 5-20µg/mL. Immunohistochemistry in formalin fixed frozen section: 5-20µg/mL. Immunohistochemistry in paraffin section: 5-20µg/mL. Optimal working dilutions must be determined by end user
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫印迹(免疫印迹)
image3头 :
免疫组化(免疫组化)
其它信息1 :
Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant TFR (Arg572~Trp757) expressed in E.coli.
其他信息2 :
Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2052125
NCBI GI登录号 :
11596855
NCBI登录号 :
NP_035768.1
NCBI基因登录号 :
NM_011638.4
UniProt数据库登录号 :
Q62351
NCBI分子量 :
85,731 Da
NCBI信号通路 :
Clathrin Derived Vesicle Budding Pathway (366623); Endocytosis Pathway (102286); Endocytosis Pathway (102181); Golgi Associated Vesicle Biogenesis Pathway (366624); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489); Membrane Trafficking Pathway (366619); Phagosome Pathway (153914); Phagosome Pathway (153859); Trans-Golgi Network Vesicle Budding Pathway (366622)
NCBI总结 :
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis. [provided by RefSeq, Sep 2015]
UniProt数据库总结 :
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Protein type: Cell surface; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 16 B3 16 23.06 cM. Cellular Component: basolateral plasma membrane; blood microparticle; cell surface; clathrin-coated pit; cytoplasm; cytoplasmic vesicle; early endosome; endosome; endosome membrane; external side of plasma membrane; extracellular exosome; extracellular region; extracellular space; HFE-transferrin receptor complex; integral component of membrane; integral component of plasma membrane; membrane; mitochondrion; nucleus; perinuclear region of cytoplasm; plasma membrane; recycling endosome; recycling endosome membrane. Molecular Function: chaperone binding; double-stranded RNA binding; Hsp70 protein binding; identical protein binding; iron ion transmembrane transporter activity; protein binding; protein homodimerization activity; RNA binding; transferrin receptor activity; transferrin transmembrane transporter activity. Biological Process: cellular iron ion homeostasis; cellular response to extracellular stimulus; cellular response to iron ion; endocytosis; osteoclast differentiation; positive regulation of B cell proliferation; positive regulation of bone resorption; positive regulation of isotype switching; positive regulation of T cell proliferation; receptor internalization; receptor-mediated endocytosis; transferrin transport
尺寸1 :
0.01毫克
价格1 :
110美元
尺寸2 :
0.02毫克
价格2 :
125
size3 :
0.05毫克
价格3 :
175
size4 :
0.1毫克
price4 :
225
size5 :
0.2毫克
price5 :
330
size6 :
1毫克
price6 :
785
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。