产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
生物素链接抗体乙2(b2M)
目录 :
MBS2006843
规格 :
0.1毫克
价格 :
230美元
克隆性 :
多克隆
宿主 :
共轭标签 :
生物素
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS2006843 图像 1
(Figure. Western Blot; Sample: Recombinant protein.)
产品信息
目录号 :
MBS2006843
产品类型 :
抗体
产品全称 :
生物素链接抗体乙2(b2M)
产品简称 :
[乙2(b2M)]
其他名称 :
[beta-2-microglobulin; Beta-2-microglobulin; beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules; beta-2-microglobulin]
产品基因名称 :
[b2M]
其他基因名称 :
[B2M;B2M]
UniProt数据库进入名 :
B2 MG_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
小鼠
序列长度 :
119
特异性 :
The antibody is a rabbit polyclonal antibody raised against b2M conjugated to biotin. It has been selected for its ability to recognize b2M in immunohistochemical staining andwestern blotting.
纯度 :
Antigen-specific Affinity Chromatography.
形式 :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
浓度 :
200微克/毫升
储存稳定性 :
Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition
检测过的应用 :
免疫印迹;免疫细胞化学;免疫组化-P;免疫组化-F;IF;酶联免疫吸附测定
应用笔记 :
Western blotting: 0.5-2ug/ml. Immunocytochemistry in formalin fixed cells: 5-20ug/ml. Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml. Immunohistochemistry in paraffin section: 5-20ug/ml. Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml. Optimal working dilutions must be determined by end user.
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Source: Antibody labeling. Traits: Liquid. Immunogen: Recombinant b2M (Gln22~Met119) expressed in E.coli.
其他信息2 :
Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2002465
产品种类 :
生物素抗体
NCBI GI登录号 :
4757826
NCBI登录号 :
NP_004039.1
NCBI基因登录号 :
NM_004048.2
UniProt数据库登录号 :
P61769
NCBI分子量 :
13,715 Da
NCBI信号通路 :
Adaptive Immune System Pathway (366160); Amyloids Pathway (366238); Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway (366163); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Antigen Processing-Cross Presentation Pathway (477122); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cytokine Signaling In Immune System Pathway (366171); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550)
NCBI总结 :
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
UniProt数据库总结 :
B2M: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Heterodimer of an alpha chain and a beta chain. Beta-2- microglobulin is the beta-chain of major histocompatibility complex class I molecules. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. Belongs to the beta-2-microglobulin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 15q21.1. Cellular Component: Golgi membrane; Golgi apparatus; extracellular space; phagocytic vesicle membrane; focal adhesion; membrane; endoplasmic reticulum lumen; early endosome membrane; cytoplasm; plasma membrane; extracellular region; MHC class I protein complex; external side of plasma membrane. Molecular Function: identical protein binding; protein binding. Biological Process: response to drug; regulation of immune response; viral reproduction; positive regulation of T cell mediated cytotoxicity; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; T cell differentiation in the thymus; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of defense response to virus by virus; retinal homeostasis; iron ion homeostasis; antigen processing and presentation of peptide antigen via MHC class I; response to cadmium ion; response to molecule of bacterial origin; antigen processing and presentation of exogenous peptide antigen via MHC class I; innate immune response; protein refolding; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent. Disease: Hypoproteinemia, Hypercatabolic
尺寸1 :
0.1毫克
价格1 :
230美元
尺寸2 :
0.2毫克
价格2 :
345
size3 :
1毫克
价格3 :
815
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。