产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
N-Acetyltransferase 8 Like Protein (NAT8L) Polyclonal Antibody
目录 :
MBS2032599
规格 :
0.01毫克
价格 :
115美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS2032599 图像 1
Western Blot: Sample: Recombinant protein.
图像 2 :
MyBioSource MBS2032599 图像 2
DAB staining on fromalin fixed paraffin- embedded brain tissue)
产品信息
目录号 :
MBS2032599
产品类型 :
抗体
产品全称 :
N-Acetyltransferase 8 Like Protein (NAT8L) Polyclonal Antibody
产品简称 :
[N-Acetyltransferase 8 Like Protein]
产品名称同义词 :
[Hcml3; CML3; NAA synthetase; N-acetylaspartate synthetase; Camello-like protein 3]
其他名称 :
[N-acetylaspartate synthetase; N-acetylaspartate synthetase; N-acetylaspartate synthetase; N-acetyltransferase 8 like; Camello-like protein 3; N-acetyltransferase 8-like protein]
产品基因名称 :
[NAT8L]
其他基因名称 :
[NAT8L;NAT8L;CML3;NACED;NAT8-LIKE;CML3;NAA合成]
克隆性 :
多克隆
宿主 :
纯度 :
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
形式 :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
浓度 :
0.57毫克/毫升
储存稳定性 :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫细胞化学(免疫细胞化学), 免疫沉淀(免疫沉淀)
应用笔记 :
Western blotting: 0.5-2 ug/mL;1:280-1100. Immunohistochemistry: 5-20 ug/mL;1:28-110. Immunocytochemistry: 5-20 ug/mL;1:28-110. Optimal working dilutions must be determined by end user.
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫组化(免疫组化)
其它信息1 :
Organism Species: Homo sapiens (Human). Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant NAT8L (Met1~Glu302) expressed in E.coli
NCBI GI登录号 :
263192221
NCBI登录号 :
NP_848652.2
NCBI基因登录号 :
NM_178557.3
UniProt数据库登录号 :
Q8N9F0
NCBI信号通路 :
Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Metabolic Pathways (132956); Metapathway Biotransformation (198837)
NCBI总结 :
This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010]
UniProt数据库总结 :
NAT8L: Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. Defects in NAT8L are the cause of N-acetylaspartate deficiency (NACED). A metabolic disorder resulting in truncal ataxia, marked developmental delay, seizures, and secondary microcephaly. Belongs to the camello family. Protein type: Acetyltransferase; EC 2.3.1.17; Membrane protein, integral. Chromosomal Location of Human Ortholog: 4p16.3. Cellular Component: cytoplasm; integral component of membrane; mitochondrial matrix; mitochondrial membrane; mitochondrion; rough endoplasmic reticulum membrane. Molecular Function: aspartate N-acetyltransferase activity. Biological Process: amino acid biosynthetic process. Disease: N-acetylaspartate Deficiency
尺寸1 :
0.01毫克
价格1 :
115美元
尺寸2 :
0.02毫克
价格2 :
135
size3 :
0.05毫克
价格3 :
190
size4 :
0.1毫克
price4 :
245
size5 :
0.2毫克
price5 :
370
size6 :
1毫克
price6 :
880
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。