产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
ADH5, 1-374aa, 人类, 多聚组氨酸标签, 大肠杆菌
目录 :
MBS204610
规格 :
0.1毫克
价格 :
310美元
更多信息或购买 :
产品信息
目录号 :
MBS204610
产品类型 :
重组蛋白
产品全称 :
ADH5, 1-374aa, 人类, 多聚组氨酸标签, 大肠杆菌
产品简称 :
ADH5
产品名称同义词 :
Alcohol dehydrogenase class-3; ADHX; FDH
其他名称 :
alcohol dehydrogenase class-3; Alcohol dehydrogenase class-3; alcohol dehydrogenase class-3; S-(hydroxymethyl)glutathione dehydrogenase; alcohol dehydrogenase (class III), chi polypeptide; alcohol dehydrogenase class chi chain; alcohol dehydrogenase class-III; formaldehyde dehydrogenase; glutathione-dependent formaldehyde dehydrogenase; alcohol dehydrogenase 5 (class III), chi polypeptide; Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase (EC:1.1.1.-); FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase (EC:1.1.1.284)
产品基因名称 :
ADH5
其他基因名称 :
ADH5;ADH5;FDH;ADHX;ADH-3;FALDH;GSNOR;GSH-FDH;FALDH;FDH;GSH-FDH
UniProt数据库进入名 :
ADHX_HUMAN
序列长度 :
374
序列 :
MGSSHHHHHH SSGLVPRGSH MGSHMANEVI KCKAAVAWEA GKPLSIEEIE VAPPKAHEVR IKIIATAVCH TDAYTLSGAD PEGCFPVILG HEGAGIVESV GEGVTKLKAG DTVIPLYIPQ CGECKFCLNP KTNLCQKIRV TQGKGLMPDG TSRFTCKGKT ILHYMGTSTF SEYTVVADIS VAKIDPLAPL DKVCLLGCGI STGYGAAVNT AKLEPGSVCA VFGLGGVGLA VIMGCKVAGA SRIIGVDINK DKFARAKEFG ATECINPQDF SKPIQEVLIE MTDGGVDYSF ECIGNVKVMR AALEACHKGW GVSVVVGVAA SGEEIATRPF QLVTGRTWKG TAFGGWKSVE SVPKLVSEYM SKKIKVDEFV THNLSFDEIN KAFELMHSGK SIRTVVKI
纯度 :
> 90% by SDS - PAGE
形式 :
液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH7.5)含20% 甘油0.1M氯化钠, 1mM DTT
浓度 :
1.0毫克/毫升(由布拉德福德Bradford检测确定)
储存稳定性 :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
检测过的应用 :
十二烷基磺酸钠-PAGE
其它信息1 :
Antigen Species: Human. Tag: His-tag
其他信息2 :
Expression System: E Coli
产品种类 :
信号转导
产品描述 :
ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. Recombinant human ADH5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
产品引用 :
Zhang,X. et al. (2010) Carcinogenesis 31 (12), 2118-2123. Shimada,M. et al. (2010) Hum. Genet. 128 (4), 433-441
NCBI GI登录号 :
71565154
NCBI登录号 :
NP_000662
NCBI基因登录号 :
NM_000671.4
NCBI分子量 :
42.3 kDa (398aa), confirmed by MALDI-TOF
NCBI信号通路 :
Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Degradation Of Aromatic Compounds Pathway 843021!!Degradation Of Aromatic Compounds Pathway 717401!!Drug Metabolism - Cytochrome P450 Pathway 83032!!Drug Metabolism - Cytochrome P450 Pathway 427!!Fatty Acid Degradation Pathway 82935!!Fatty Acid Degradation Pathway 296
NCBI总结 :
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
规格 :
0.1毫克
价格 :
310美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。