抗体

APC链接多克隆抗体转谷氨酰胺酶2, 组织(TGM2)

MBS2059642

0.1毫克

295美元

多克隆

兔

APC

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗体

APC链接多克隆抗体转谷氨酰胺酶2, 组织(TGM2)

[转谷氨酰胺酶2(TGM2)]

[tTG; TG2; C Polypeptide, Protein-Glutamine-Gamma-Glutamyltransferase; Transglutaminase C; Transglutaminase H]

[转谷氨酰胺酶2;蛋白谷氨酸γ-谷氨酰转移酶2;蛋白谷氨酸γ-谷氨酰转移酶2;转谷氨酰胺酶2;组织转谷氨酰胺酶;转谷氨酰胺酶C;TG(C);TGC;TGase C;转谷氨酰胺酶H;TGase H;转谷氨酰胺酶2;TGase-2]

[TGM2]

[TGM2;TGM2;TGC;TG(C);TG(C);TGC;TGase C;TGase H;TGase-2]

多克隆

兔

Antigen-specific Affinity Chromatography.

Supplied as solution form 0.02% NaN 3 , 10 mM Tris, 150 mM NaCI, pH 8.2, 50% glycerol 0.02% NaN 3

0.34毫克/毫升

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

免疫印迹(免疫印迹);免疫细胞化学(免疫组化);免疫细胞化学(免疫细胞化学);免疫沉淀(免疫沉淀)

Western blotting: 0.5-2 ug/mL;1:170-680. Immunohistochemistry: 5-20 ug/mL;1:17-68. Immunocytochemistry: 5-20 ug/mL;1:17-68. Optimal working dilutions must be determined by end user

基因敲除验证

Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: APC. Traits: Liquid. Immunogen: Recombinant TGM2 (Met1~Ala687) expressed in E.coli.

50593093

AAT79353.1

Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Thromboxane A2 Receptor Signaling Pathway (138060)

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

TGM2: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Is the autoantigen in coeliac disease and plays a role in apoptosis, cellular differentiation and matrix stabilisation. Three alternatively spliced isoforms have been described. Protein type: EC 2.3.2.13; Transferase. Chromosomal Location of Human Ortholog: 20q11.23. Cellular Component: cytosol; extracellular matrix; focal adhesion; intrinsic to plasma membrane; mitochondrion. Molecular Function: protein binding; protein-glutamine gamma-glutamyltransferase activity. Biological Process: apoptotic cell clearance; elevation of mitochondrial calcium ion concentration; positive regulation of apoptosis; positive regulation of cell adhesion; reduction of endoplasmic reticulum calcium ion concentration

0.1毫克

295美元

0.2毫克

470

1毫克

1120