产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
大鼠抗MOUSE CD16/CD32:FITC
目录 :
MBS210943
规格 :
0.1毫克
价格 :
205美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
FCR4G8
反应物种 :
小鼠
应用 :
流式细胞仪, 流式细胞仪
更多信息或购买 :
产品信息
目录号 :
MBS210943
产品类型 :
抗体
产品全称 :
大鼠抗MOUSE CD16/CD32:FITC
产品简称 :
CD16/CD32
其他名称 :
low affinity immunoglobulin gamma Fc region receptor II-b isoform 2; Low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; Fc gamma RIIB; Fc-gamma-RII; FcgammaRIIB; fc gamma receptor IIB; fc-gamma RII; fc-gamma-RIIB; igG Fc receptor II beta; lymphocyte antigen 17; Fc receptor, IgG, low affinity IIb; Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII; IgG Fc receptor II beta; Lymphocyte antigen 17; Ly-17; CD_antigen: CD32
产品基因名称 :
CD16/CD32
其他基因名称 :
Fcgr2b; Fcgr2; CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik; Fcgr2b; Ly-17; Fc-gamma RII; Fc-gamma-RIIB; FcRII; Ly-17
UniProt数据库进入名 :
FCGR2_MOUSE
克隆性 :
单克隆
抗体亚型 :
IgG2b
克隆 :
FCR4G8
宿主 :
大鼠
序列长度 :
293
形式 :
FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
浓度 :
IgG浓度0.1毫克/毫升
储存稳定性 :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
检测过的应用 :
流式细胞仪(FC/流式细胞仪)
应用笔记 :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
其它信息1 :
Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G
其他信息2 :
Immunogen: PU5 1.8 IOE7 Balb/c mouse cell line. Fusion Partners: Cells from immunised rats were fused with cells of the mouse P3X63-Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Mouse
产品描述 :
Rat anti Mouse CD16/CD32 antibody, clone FCR4G8 recognizes an epitope expressed by the murine low affinity Fc receptors, Fc gamma III (CD16) and Fc gamma II (CD32). In the mouse only the transmembrane form of CD16 is reported to exist, which is expressed on macrophages, NK cells, granulocytes, myeloid precursors, and subpopulations of T lymphocytes. CD32 is primarily expressed on cells of the myeloid lineage and also on mature B lymphocytes.
NCBI GI登录号 :
6857783
NCBI登录号 :
NP_034317.1
NCBI基因登录号 :
NM_010187.2
NCBI分子量 :
Da
NCBI信号通路 :
B Cell Receptor Signaling Pathway (198285); B Cell Receptor Signaling Pathway (83278); B Cell Receptor Signaling Pathway (492); FCGR Activation Pathway (1110768); Fc Gamma R-mediated Phagocytosis Pathway (114297); Fc Gamma R-mediated Phagocytosis Pathway (106590); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (1110767); Immune System Pathway (1110668); Innate Immune System Pathway (1110697); Measles Pathway (213308)
UniProt数据库总结 :
FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed. Protein type: Membrane protein, integral; Oncoprotein; Cell surface. Cellular Component: recycling endosome; cell surface; cytoskeleton; membrane; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region; integral to membrane; lipid raft; external side of plasma membrane. Molecular Function: protein binding; IgG binding; receptor signaling protein activity; immunoglobulin binding. Biological Process: receptor-mediated endocytosis; negative regulation of phagocytosis; negative regulation of interleukin-10 production; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; defense response; negative regulation of B cell proliferation; endocytic recycling; negative regulation of type I hypersensitivity; mast cell activation; negative regulation of neutrophil apoptosis; negative regulation of humoral immune response mediated by circulating immunoglobulin; cell surface receptor linked signal transduction; response to bacterium; positive regulation of phagocytosis; negative regulation of immunoglobulin production; immune complex clearance; negative regulation of inflammatory response to antigenic stimulus; immune response; immunoglobulin mediated immune response; phagocytosis, engulfment
尺寸1 :
0.1毫克
价格1 :
205美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。