抗体

MOUSE抗人类CD16

MBS212047

0.2毫克

415美元

单克隆

小鼠

未共轭

LNK16

免疫沉淀, 流式细胞仪, 流式细胞仪

抗体

MOUSE抗人类CD16

CD16

low affinity immunoglobulin gamma Fc region receptor III-B isoform 2; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma receptor IIIb (CD 16); fc-gamma RIII-beta; fc-gamma RIIIb; igG Fc receptor III-1; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b

CD16

FCGR3B;FCGR3B;CD16;FCG3;CD16b;FCGR3;FCR-10;FCRIII;FCRIIIb;CD16B;FCG3;FCGR3;IGFR3;Fcγ受体Ⅲ;Fc丙RIIIb;FcRIII;FcRIIIb

FCG3B_HUMAN

单克隆

IgG1

LNK16

小鼠

233

纯化。 纯化IgG-液体

IgG浓度1.0毫克/毫升

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

流式细胞仪(FC/流式细胞仪), 免疫沉淀(免疫沉淀)

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul human whole blood. Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/20

Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by ion exchange chromatography

Immunogen: Normal human peripheral blood granulocytes. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human

Mouse anti Human CD16 antibody, clone LNK16 recognizes CD16, a 50-65kDa cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Mouse anti Human CD16 antibody, clone LNK16 has been reported to block the binding of IgG to the CD16 molecule (Tamm and Schmidt 1996).

132814489

NP_000561.3

NM_000570.4

26,216 Da

Leishmaniasis Pathway (144181); Leishmaniasis Pathway (144028); Natural Killer Cell Mediated Cytotoxicity Pathway (83079); Natural Killer Cell Mediated Cytotoxicity Pathway (490); Osteoclast Differentiation Pathway (193147); Osteoclast Differentiation Pathway (193096); Phagosome Pathway (153910); Phagosome Pathway (153859); Staphylococcus Aureus Infection Pathway (172846); Staphylococcus Aureus Infection Pathway (171867)

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

0.2毫克

415美元