抗体

大鼠抗MOUSE CD11b

MBS216534

0.025毫克

145美元

单克隆

大鼠

未共轭

5C6

免疫细胞化学, 免疫沉淀, 流式细胞仪, 流式细胞仪

抗体

大鼠抗MOUSE CD11b

CD11b

Integrin alpha-M; Integrin alpha-M; integrin alpha-M; CD11 antigen-like family member B; CD11B (p170); CR-3 alpha chain; Mac-1 alpha; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; leukocyte adhesion receptor MO1; macrophage antigen alpha; integrin alpha M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; CD_antigen: CD11b

CD11b

Itgam; Itgam; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik

ITAM_MOUSE

单克隆

IgG2b

5C6

大鼠

1153

纯化。 纯化IgG-液体

IgG浓度1毫克/毫升

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Maximum Dilution: 1/100

Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by ion exchange chromatography

Buffer Solution: Phosphate buffered saline. Target Species: Mouse

Rat anti Mouse CD11b antibody, clone 5C6 recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. MBS216530 immunoprecipitates a heterodimer of 165 and 95kD. Rat anti Mouse CD11b antibody, clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

124956

P05555.2

P05555

115,196 Da

Amoebiasis Pathway (167330); Amoebiasis Pathway (167191); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (1110059); Extracellular Matrix Organization Pathway (1110302); Focal Adhesion Pathway (198353); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489); Hemostasis Pathway (1110026)

ITGAM: a single-pass type I membrane protein of the integrin alpha chain family. Implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Also known as CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. A receptor for fibrinogen, factor X and ICAM1. Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2. Predominantly expressed in monocytes and granulocytes. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion. Cellular Component: cell surface; membrane; integral to membrane; integrin complex; nucleus; external side of plasma membrane. Molecular Function: heparin binding; heparan sulfate proteoglycan binding; opsonin binding; protein heterodimerization activity; metal ion binding; glycoprotein binding. Biological Process: integrin-mediated signaling pathway; neutrophil chemotaxis; leukocyte adhesion; cell-cell adhesion; microglia development; cellular extravasation; activated T cell proliferation; cell adhesion; leukocyte migration during inflammatory response

0.025毫克

145美元