抗体

羊抗人类C1q:HRP

MBS220377

1毫升

380美元

多克隆

羊

HRP

酶联免疫吸附测定, 酶免疫法

抗体

羊抗人类C1q:HRP

C1q

C1QG

complement C1q subcomponent subunit A; Complement C1q subcomponent subunit A; complement C1q subcomponent subunit A; complement component 1, q subcomponent, alpha polypeptide; complement component C1q, A chain; complement component 1, q subcomponent, A chain

C1q

C1QA;C1QA

C1QA_HUMAN

多克隆

IgG

羊

245

Sheep anti human C1q antibody may crossreact with C1q in other species. Sheep anti Human C1q antibody recognizes human C1q, a sub-component of complement C1. C1q associates with complemtn components C1r adn C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erthematosus and glomerulonephritis (Troedson et al. 2013)

HRP. Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid

IgG浓度1.0毫克/毫升

Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

酶联免疫吸附测定(EIA)

ELISA: Minimum Dilution: 1/100; Maximum Dilution: 1/400

Perservative Stabilisers: 0.01% Thiomersal. HRP Stabiliser. Immunogen: Human C1q

Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antisera to human C1q were raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared from whole serum by protein G affinity chromatography. Target Species: Human

Sheep anti Human C1q antibody recognizes human C1q, a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis (Troedson et al. 2013). Sheep anti human C1q antibody may cross react with C1q in other species.

7705753

NP_057075.1

NM_015991.2

26,017 Da

Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Classical Antibody-mediated Complement Activation Pathway (106409); Complement Activation, Classical Pathway (198823); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); Immune System Pathway (106386)

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq, Jul 2008]

C1QA iso2: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2 )-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1p36.12. Cellular Component: collagen; extracellular region; complement component C1 complex. Molecular Function: protein binding. Biological Process: cell-cell signaling; innate immune response; complement activation, classical pathway; complement activation. Disease: C1q Deficiency

1毫升

380美元