抗体

山羊抗人类转铁蛋白

MBS221751

1毫克

235美元

多克隆

山羊

未共轭

酶联免疫吸附测定, 酶免疫法

抗体

山羊抗人类转铁蛋白

转铁蛋白

serotransferrin; Serotransferrin; serotransferrin; beta-1 metal-binding globulin; siderophilin; transferrin; Beta-1 metal-binding globulin; Siderophilin

TF;TF;TFQTL1;PRO1557;PRO2086;转铁蛋白

TRFE_HUMAN

多克隆

IgG

山羊

698

纯化。 纯化IgG-液体

IgG浓度1.0毫克/毫升

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

酶联免疫吸附测定(EIA)

ELISA: Minimum Dilution: 1/100; Maximum Dilution: 1/10,000

Perservative Stabilisers: 0.09% Sodium Azide

Immunogen: Purified human transferrin. Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antisera to human transferrin were raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human

Goat anti Human Transferrin antibody recognizes human transferrin, an iron binding glycoprotein of 79kD. Transferrin has an important role in transporting iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body

4557871

NP_001054.1

NM_001063.3

P02787

77,064 Da

EPHB Forward Signaling Pathway (138047); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050)

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]

TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: extracellular space; cell surface; cytoplasmic membrane-bound vesicle; early endosome; extracellular region; coated pit; recycling endosome; perinuclear region of cytoplasm; endocytic vesicle; late endosome; apical plasma membrane; basal plasma membrane; endosome membrane; vesicle. Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding. Biological Process: retinal homeostasis; platelet activation; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport. Disease: Atransferrinemia

1毫克

235美元