产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
大鼠抗MOUSE CD16
目录 :
MBS224798
规格 :
0.25毫克
价格 :
430美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
[AT154-2]
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
产品信息
目录号 :
MBS224798
产品类型 :
抗体
产品全称 :
大鼠抗MOUSE CD16
产品简称 :
[CD16]
产品名称同义词 :
[FcRIII]
其他名称 :
[Low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III; low affinity immunoglobulin gamma Fc region receptor III; Fc receptor, IgG, low affinity III; Fc-gamma RIII; FcRIII; CD_antigen: CD16]
产品基因名称 :
[CD16]
其他基因名称 :
[Fcgr3;Fcgr3;CD16;IgG Fc受体III;FcRIII]
UniProt数据库进入名 :
FCGR3_MOUSE
克隆性 :
单克隆
抗体亚型 :
IgG2b
克隆 :
[AT154-2]
宿主 :
大鼠
特异性 :
Rat anti Mouse CD16 anitbody, clone AT154-2, recognizes CD16, also known as FcRIII. CD16 is a low affiniity activatory receptor which interacts preferentially with mouse IgG1, IgG2a and IgG2b immune complexes and is involved in various effector functions including phagocytosis, NK antibody dependent cellular cytotoxicity and the release of inflammatory mediators. In mice, CD16 is expressed on macrophages, NK cells, granulocytes, myeloid precursors and subpopulations of T lymphocytes.
形式 :
纯化IgG-液体, 三羟甲基氨基甲烷缓冲盐液
储存稳定性 :
Shelf Life: 18 months form date of dispatch. Store at 4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
检测过的应用 :
Flow Cytometry (FC), Immunohistology - Frozen
应用笔记 :
Flow Cytometry: 1/10*. Immunohistology - Frozen: 1/100 - 1/1000. *Use 10ul of the suggested working dilution to label 1x10 6 cells in 100ul. Where this product has not been tested in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
其它信息1 :
Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant. Preservative Stabilisers: 0.09 Sodium Azide (NaN 3 ). Concentration: IgG concentration 1.0 mg/ml. Target Species: Mouse. Immunogen: HEK293F cell expressing CD16 and gamma chain. Fusion Partners: Spleen cells from immunised rats were fused with cells of the NS-1 myeloma cell line
NCBI GI登录号 :
119877
NCBI登录号 :
P08508.1
UniProt数据库登录号 :
P08508
NCBI信号通路 :
Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (1323740); Immune System Pathway (1323639); Innate Immune System Pathway (1323671); Leishmaniasis Pathway (144183); Leishmaniasis Pathway (144028); Osteoclast Differentiation Pathway (193149); Osteoclast Differentiation Pathway (193096); Phagosome Pathway (153914); Phagosome Pathway (153859); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (1323741)
UniProt数据库总结 :
FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells. Protein type: Membrane protein, integral; Cell surface; Receptor, misc. Cellular Component: external side of plasma membrane; integral to membrane; membrane; plasma membrane. Molecular Function: IgG binding; IgG receptor activity. Biological Process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; mast cell activation; neutrophil chemotaxis; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of type I hypersensitivity; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; regulation of immune response; serotonin secretion
尺寸1 :
0.25毫克
价格1 :
430美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。