MyBioSource

蛋白

重组人类FGF BASIC

MBS232289

0.05毫克

430美元

MBS232289

重组蛋白

重组人类FGF BASIC

FGF BASIC

fibroblast growth factor 2; Fibroblast growth factor 2; fibroblast growth factor 2; basic fibroblast growth factor bFGF; heparin-binding growth factor 2; prostatropin; fibroblast growth factor 2 (basic); Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2

FGF

纤维生长因子2;纤维生长因子2;BFGF;FGFB;FGF-2;HBGF-2;FGFB;FGF-2;bFGF;HBGF-2

FGF2_HUMAN

288

>95% by SDS PAGE and HPLC analysis

Purified recombinant protein expressed in E Coli - lyophilised

Total protein concentration 0.1 mg/ml after reconstitution.

Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 3 months from date of reconstitution.

ELISA (EIA), Functional Assays (FN), Western Blot (WB)

ELISA: Minimum Dilution: 0.2; Maximum Dilution: 0.4 ng/well;. Functional Assays: Minimum Dilution: 0.1; Maximum Dilution: 10 ng/ml;. Western Blotting: Minimum Dilution: 1.5; Maximum Dilution: 3.0 ng/lane

Reconstitution: Reconstitute with 0.5ml Tris (5mM, pH7.6). Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. Further dilutions may be prepared in a buffer containing a carrier protein (eg 0.1% BSA).

Buffer Solution: TRIS buffered saline. Activity: 2 x 106 units/mg. Target Species: Human

Recombinant Human FGF basic represents the C-terminal protion of human fibroblast growth factor 2 (A135 - S288). Fibroblast growth factor basic (FGF basic), also known as FGF 2, is a heparin binding growth factor which has stimulatory activity on a range of cells of mesenchymal, neuroectodermal and endothelial origin.Note: FGF basic is sensitive to acidic conditions.

153285461

NP_001997.5

NM_002006.4

P09038

Protein Molecular Weight: 17.2kD (154 amino acid sequence)

Activated Point Mutants Of FGFR2 Pathway 645281!!Adaptive Immune System Pathway 366160!!Angiogenesis Pathway 198772!!Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!Cardiac Progenitor Differentiation Pathway 712094!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Developmental Biology Pathway 477129!!Disease Pathway 530764

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]

0.05毫克

430美元