产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
兔多抗人类ITGAX/CD11c
目录 :
MBS240164
规格 :
0.05毫克
价格 :
495美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
目录号 :
MBS240164
产品类型 :
抗体
产品全称 :
兔多抗人类ITGAX/CD11c
产品简称 :
ITGAX/CD11c
产品名称同义词 :
Anti-ITGAX / CD11c Antibody (Internal) IHC-plus; ITGAX; CD11c antigen; Integrin alpha-X; Leu M5; alpha subunit; p150 95 integrin alpha chain; SLEB6; CD11C; Leu M5; Human ITGAX; CD11c
其他名称 :
integrin alpha-X isoform 2; Integrin alpha-X; integrin alpha-X; leu M5, alpha subunit; p150 95 integrin alpha chain; CD11 antigen-like family member C; leukocyte adhesion receptor p150,95; myeloid membrane antigen, alpha subunit; leukocyte surface antigen p150,95, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c
产品基因名称 :
ITGAX
产品基因名称同义词 :
CD11c
其他基因名称 :
ITGAX;ITGAX;CD11C;SLEB6;CD11C
UniProt数据库进入名 :
ITAX_HUMAN
克隆性 :
多克隆
宿主 :
反应物种 :
大猩猩, 人类
序列长度 :
1163
特异性 :
Human CD11c. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
纯度 :
Immunoaffinity Purified
形式 :
PBS, 0.1% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Long term: -70 degree C; Short term: +4 degree C
检测过的应用 :
免疫组化(免疫组化-石蜡)
应用笔记 :
IHC-P (10 - 20 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
其它信息1 :
Target Species: Human. Immunogen Description: Synthetic 15 amino acid peptide from internal region of human CD11c. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (87%); Marmoset (80%).
其他信息2 :
Immunogen Type: Synthetic peptide. Immunogen: ITGAX / CD11c antibody was raised against synthetic 15 amino acid peptide from internal region of human CD11c. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (87%); Marmoset (80%). Antigen Modification: Internal
产品种类 :
Family: Integrin
产品描述 :
CD11C (ITGAX) encodes the integrin alpha X chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4).
NCBI GI登录号 :
34452173
NCBI登录号 :
NP_000878.2
NCBI基因登录号 :
NM_000887.4
UniProt数据库登录号 :
P20702
NCBI分子量 :
127,829 Da
NCBI信号通路 :
Cell Surface Interactions At The Vascular Wall Pathway (106062); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795); Hemostasis Pathway (106028); Integrin Cell Surface Interactions Pathway (106110); Integrin-mediated Cell Adhesion Pathway (198816); Regulation Of Actin Cytoskeleton Pathway (83089); Regulation Of Actin Cytoskeleton Pathway (500); Tuberculosis Pathway (213780)
NCBI总结 :
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
UniProt数据库总结 :
ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: cell surface; membrane; plasma membrane; integrin complex. Molecular Function: protein binding; metal ion binding; receptor activity. Biological Process: integrin-mediated signaling pathway; heterotypic cell-cell adhesion; organ morphogenesis; extracellular matrix organization and biogenesis; cell adhesion; blood coagulation; leukocyte migration. Disease: Systemic Lupus Erythematosus
尺寸1 :
0.05毫克
价格1 :
495美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。