产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
兔多抗人类PPP1R13L/RAI/IASPP
目录 :
MBS240529
规格 :
0.05毫克
价格 :
495美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS240529
产品类型 :
抗体
产品全称 :
兔多抗人类PPP1R13L/RAI/IASPP
产品简称 :
PPP1R13L/RAI/IASPP
产品名称同义词 :
Anti-PPP1R13L / RAI / IASPP Antibody (aa780-797) IHC-plus; PPP1R13L; IASPP; Inhibitor of ASPP protein; NFkB-interacting protein 1; NKIP1; RAI4; RAI; Retinoic acid induced 4; NFkB interacting protein 1; PPP1R13BL; Protein iASPP; RelA-associated inhibitor; PPP1R13B-like protein; Human PPP1R13L; RAI; IASPP
其他名称 :
relA-associated inhibitor; RelA-associated inhibitor; relA-associated inhibitor; protein iASPP; PPP1R13B-like protein; retinoic acid induced 4; inhibitor of ASPP protein; NFkB interacting protein 1; NFkB-interacting protein 1; inhibitor of apoptosis stimulating protein of p53; protein phosphatase 1, regulatory (inhibitor) subunit 13 like; protein phosphatase 1, regulatory subunit 13 like; Inhibitor of ASPP protein; Protein iASPP; NFkB-interacting protein 1; PPP1R13B-like protein
产品基因名称 :
PPP1R13L
产品基因名称同义词 :
RAI;IASPP
其他基因名称 :
PPP1R13L;PPP1R13L;RAI;RAI4;IASPP;NKIP1;IASPP;NKIP1;PPP1R13BL;RAI;蛋白iASPP
UniProt数据库进入名 :
IASPP_HUMAN
克隆性 :
多克隆
宿主 :
反应物种 :
人类
序列长度 :
828
特异性 :
Amino acids 780-797 of human iASPP (isoform 1) protein.
纯度 :
Immunoaffinity Purified
形式 :
0.02 M钾磷酸盐, 0.15 M氯化钠, pH值7.2, 0.01% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Store vial at -20 degree C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing.
检测过的应用 :
免疫组化(免疫组化-石蜡), 免疫荧光(IF), 免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
ELISA (1:40000 - 1:160000), IF, IHC-P (2.5 ug/ml), WB (1:1000 - 1:5000). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.
其它信息1 :
Target Species: Human. Immunogen Description: Synthetic peptide from human PPP1R13L / IASPP.
其他信息2 :
Immunogen Type: Synthetic peptide. Immunogen: PPP1R13L / RAI / IASPP antibody was raised against synthetic peptide from human PPP1R13L / IASPP. Antigen Modification: aa780-797
NCBI GI登录号 :
63003907
NCBI登录号 :
NP_006654.2
NCBI基因登录号 :
NM_006663.3
UniProt数据库登录号 :
Q8WUF5
NCBI分子量 :
89,091 Da
NCBI信号通路 :
Integrated Pancreatic Cancer Pathway (711360); TNF-alpha/NF-kB Signaling Pathway (198884); P53 Pathway (138067)
NCBI总结 :
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008]
UniProt数据库总结 :
PPP1R13L: an oncoprotein that interacts with and inhibits NF-kappaB, Sp1 and p53. Plays a central role in regulation of apoptosis and transcription. May inhibit p53 by preventing its association with ASPP1 or ASPP2, thereby suppressing the subsequent activation of apoptosis. Required for neuronal survival after axonal injury. Two alternatively spliced isoforms have been described. Isoform 1 is preferrentially found in the cytoplasm; isoform 2 is nuclear. Protein type: Phosphatase, regulatory subunit; Apoptosis; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 19q13.32. Cellular Component: intercellular bridge; cytoplasm; cell junction; nucleus. Molecular Function: identical protein binding; protein binding; transcription factor binding; transcription corepressor activity. Biological Process: transcription, DNA-dependent; apoptosis; multicellular organism growth; negative regulation of transcription from RNA polymerase II promoter; multicellular organismal homeostasis; embryonic camera-type eye development; post-embryonic development; cardiac muscle contraction; hair cycle
尺寸1 :
0.05毫克
价格1 :
495美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。