抗体

兔多抗人类内皮细胞一氧化氮合酶/eNOS

MBS241182

0.05毫克

495美元

多克隆

兔

nonconjugated

人类, 小鼠, 大鼠

免疫组化, 免疫组化-石蜡切片

抗体

兔多抗人类内皮细胞一氧化氮合酶/eNOS

内皮细胞一氧化氮合酶/eNOS

Anti-NOS3 / eNOS Antibody (C-Terminus) IHC-plus; NOS3; Constitutive NOS; CNOS; Endothelial NOS; ECNOS; NOS type III; NOSIII; EC-NOS; ENOS; Nitric oxide synthase 3; Human NOS3; eNOS

nitric oxide synthase, endothelial isoform 1; Nitric oxide synthase, endothelial; nitric oxide synthase, endothelial; cNOS; EC-NOS; NOSIII; NOS type III; endothelial NOS; constitutive NOS; nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 (endothelial cell); Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII

内皮细胞一氧化氮合酶

eNOS

内皮细胞一氧化氮合酶;内皮细胞一氧化氮合酶;eNOS;ECNOS;cNOS;eNOS;NOSIII

NOS3_HUMAN

多克隆

兔

人类, 小鼠, 大鼠

1203

肽来自C末端人的内皮细胞一氧化氮合酶

亲和纯化

PBS, pH值7.4, 0.2% BSA, 0.05% 叠氮化钠

0.2毫克/毫升

+4 degree C or -20 degree C, Avoid repeated freezing and thawing.

免疫组化(免疫组化-石蜡)

IHC-P (10 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

Target Species: Human. Immunogen Description: Synthetic peptide from human NOS3 / ENOS.

Immunogen Type: Synthetic peptide. Immunogen: NOS3 / eNOS antibody was raised against synthetic peptide from human NOS3 / ENOS. Antigen Modification: C-Terminus

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.

40254422

NP_000594.2

NM_000603.4

P29474

67,876 Da

ACE Inhibitor Pathway (198763); AGE/RAGE Pathway (698754); Angiogenesis Pathway (198772); Angiopoietin Receptor Tie2-mediated Signaling Pathway (137917); Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Corticotropin-releasing Hormone Pathway (920957); Disease Pathway (530764)

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

eNOS: endothelial constitutive nitric oxide synthase. Synthesizes nitric oxide (NO) from arginine and oxygen, which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Induced in humans by caloric restriction. Stimulated by calcium/calmodulin. Inhibited by NOSIP and NOSTRIN. Protein type: EC 1.14.13.39; Oxidoreductase; Amino Acid Metabolism - arginine and proline. Chromosomal Location of Human Ortholog: 7q36. Cellular Component: Golgi membrane; cytoskeleton; cytoplasm; plasma membrane; caveola; nucleus; cytosol. Molecular Function: actin monomer binding; calmodulin binding; protein binding; FAD binding; NADPH-hemoprotein reductase activity; nitric-oxide synthase activity; FMN binding; iron ion binding; heme binding; NADP binding; cadmium ion binding. Biological Process: regulation of systemic arterial blood pressure by endothelin; negative regulation of potassium ion transport; negative regulation of muscle hyperplasia; positive regulation of vasodilation; nitric oxide metabolic process; negative regulation of cell proliferation; regulation of blood pressure; regulation of the force of heart contraction by chemical signal; negative regulation of hydrolase activity; lipopolysaccharide-mediated signaling pathway; negative regulation of blood pressure; angiogenesis; regulation of blood vessel size; nitric oxide biosynthetic process; interaction with host; mitochondrion organization and biogenesis; negative regulation of calcium ion transport; in utero embryonic development; positive regulation of guanylate cyclase activity; regulation of sodium ion transport; ovulation from ovarian follicle; positive regulation of angiogenesis; response to heat; arginine catabolic process; endothelial cell migration; blood vessel remodeling; regulation of nitric-oxide synthase activity; blood coagulation; vascular endothelial growth factor receptor signaling pathway; nitric oxide mediated signal transduction; lung development; smooth muscle hyperplasia. Disease: Preeclampsia/eclampsia 1; Alzheimer Disease; Hypertension, Essential; Stroke, Ischemic

0.05毫克

495美元