抗体

山羊多克隆抗人类GFAP

MBS241916

0.05毫克

495美元

多克隆

山羊

未共轭

人类, 大鼠, 狗, 鸡, 牛

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

山羊多克隆抗人类GFAP

GFAP

Anti-GFAP Antibody (C-Terminus) IHC-plus; GFAP; Human GFAP

glial fibrillary acidic protein isoform 1; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein

GFAP

GFAP;GFAP;GFAP

GFAP_HUMAN

多克隆

山羊

Human, Monkey, Rat, Bat, Bovine, Horse, Rabbit. Predicted Reactivity: Mouse, Dog, Pig, Chicken

432

人类GFAP

Immunoaffinity Purified

三羟甲基氨基甲烷缓冲盐液, pH值7.3, 0.5% BSA, 0.02% 叠氮化钠

0.5毫克/毫升

Store at -20 degree C. Minimize freezing and thawing.

免疫组化(免疫组化-石蜡), 免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)

ELISA (1:32000), IHC-P (5 ug/ml), WB (1 - 3 ug/ml). Usage: Immunohistochemistry: MBS241916 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS241916 was determined to be 5 ug/ml.

Target: GFAP. Target Species: Human. Immunogen Description: Synthetic peptide C-DGEVIKESKQEHKD from the C-terminus of human GFAP (NP_002046.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Rat, Bat, Bovine, Elephant, Horse, Rabbit (100%). Antigen Type: Synthetic peptide

Immunogen: GFAP antibody was raised against synthetic peptide C-DGEVIKESKQEHKD from the C-terminus of human GFAP (NP_002046.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Rat, Bat, Bovine, Elephant, Horse, Rabbit (100%); Mouse, Dog, Pig, Turkey, Chicken (93%); Opossum, Lizard (86%). Antigen Modification: C-Terminus

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

4503979

NP_002046.1

NM_002055.4

P14136

Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (530744); Signal Transduction Pathway (477114); Signaling By ERBB4 Pathway (530741); Spinal Cord Injury Pathway (739007)

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: membrane; cytoplasm; intermediate filament; cytosol. Molecular Function: integrin binding; structural constituent of cytoskeleton; kinase binding. Biological Process: Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; regulation of neurotransmitter uptake; response to wounding; intermediate filament organization; neurite regeneration; astrocyte development. Disease: Alexander Disease

0.05毫克

495美元