产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
Mouse Monoclonal [clone A53-B/A2.26] (IgG2a,l) to Human KRT19 / CK19 / Cytokeratin 19
目录 :
MBS245294
规格 :
0.125毫升
价格 :
495美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A53-B/A2.26
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS245294
产品类型 :
抗体
产品全称 :
Mouse Monoclonal [clone A53-B/A2.26] (IgG2a,l) to Human KRT19 / CK19 / Cytokeratin 19
产品简称 :
KRT19/CK19/细胞角蛋白19
产品名称同义词 :
Anti-KRT19 / CK19 / Cytokeratin 19 Antibody (aa312-335, clone A53-B/A2.26) IHC-plus; KRT19; CK19; Cytokeratin 19; Cytokeratin-19; Keratin 19; Keratin-19; CK-19; K19; K1CS; Keratin; type I; 40-kd; Human KRT19; CK19; Cytokeratin 19
其他名称 :
keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 19; keratin, type I cytoskeletal 19; CK-19; keratin-19; cytokeratin 19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament; keratin 19; Cytokeratin-19; CK-19; Keratin-19; K19
产品基因名称 :
KRT19
其他基因名称 :
KRT19;KRT19;K19;CK19;K1CS;CK-19;K19
UniProt数据库进入名 :
K1C19_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG2a, l
克隆 :
A53-B/A2.26
宿主 :
小鼠
反应物种 :
豚鼠, 人类, 小鼠, 大鼠
序列长度 :
400
特异性 :
Recognizes the rod domain of keratin 19 (40kD). Reacts with the MCF-7 cells, which are known to contain keratin 19. It shows no reaction with the cells lacking keratin 19 such as A431 and HeLa. Species cross-reactivity: Human. Weak reactivity with rat, mouse and guinea pig.
纯度 :
蛋白质G纯化
形式 :
10 mM PBS, pH值7.4, 0.2% BSA, 0.09% 叠氮化钠
浓度 :
0.2毫克/毫升
储存稳定性 :
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
检测过的应用 :
免疫组化(免疫组化-石蜡;免疫组化-冷冻), 免疫荧光(IF), 免疫印迹(免疫印迹)
应用笔记 :
IF, IHC-Fr (1 - 2 ug/ml), IHC-P (10 ug/ml), WB (2 - 4 ug/ml). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
其它信息1 :
Target Species: Human. Immunogen Description: Human breast cancer MCF-7 cells. Epitope: aa312-335 Cellular Localization: Cytoplasmic. MW of antigen: 40kD.
其他信息2 :
Immunogen: KRT19 / CK19 / Cytokeratin 19 antibody was raised against human breast cancer MCF-7 cells. Epitope: aa312-335 Cellular Localization: Cytoplasmic. MW of antigen: 40kD. Antigen Modification: aa312-335
产品描述 :
Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells.
NCBI GI登录号 :
24234699
NCBI登录号 :
NP_002267.2
NCBI基因登录号 :
NM_002276.4
UniProt数据库登录号 :
P08727
NCBI分子量 :
44,106 Da
NCBI信号通路 :
Signaling Mediated By P38-alpha And P38-beta Pathway (138012)
NCBI总结 :
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: dystrophin-associated glycoprotein complex; costamere; intermediate filament; Z disc; sarcolemma. Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; protein complex binding. Biological Process: viral reproduction; response to estrogen stimulus; sarcomere organization
尺寸1 :
0.125毫升
价格1 :
495美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。