产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
Mouse Monoclonal [clone 5E3] (IgG2b,k) to Human NPM1 / NPM / Nucleophosmin
目录 :
MBS245427
规格 :
0.05毫克
价格 :
495美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
5.00E+03
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS245427
产品类型 :
抗体
产品全称 :
Mouse Monoclonal [clone 5E3] (IgG2b,k) to Human NPM1 / NPM / Nucleophosmin
产品简称 :
NPM1 / NPM / Nucleophosmin
产品名称同义词 :
Anti-NPM1 / NPM / Nucleophosmin Antibody (aa81-294, clone 5E3) IHC-plus; NPM1; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin; B23; Nucleophosmin; Human NPM1; NPM; Nucleophosmin
其他名称 :
nucleophosmin isoform 1; Nucleophosmin; nucleophosmin; nucleolar protein NO38; nucleophosmin/nucleoplasmin family, member 1; nucleophosmin (nucleolar phosphoprotein B23, numatrin); Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
产品基因名称 :
NPM1
其他基因名称 :
NPM1;NPM1;B23;NPM;NPM;NPM
UniProt数据库进入名 :
NPM_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG2b, k
克隆 :
5.00E+03
宿主 :
小鼠
反应物种 :
人类
序列长度 :
294
纯度 :
蛋白质G纯化
形式 :
PBS, pH值7.4, 0.1% 叠氮化钠
浓度 :
1毫克/毫升
储存稳定性 :
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
检测过的应用 :
免疫组化(免疫组化-石蜡), 免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
ELISA, IHC-P (5 ug/ml), WB. Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.
其它信息1 :
Target Species: Human. Immunogen Description: Recombinant human NPM (81-294aa) purified from E Coli.
其他信息2 :
Immunogen Type: Recombinant protein. Immunogen: NPM1 / NPM / Nucleophosmin antibody was raised against recombinant human NPM (81-294aa) purified from E Coli. Antigen Modification: aa81-294
产品描述 :
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
NCBI GI登录号 :
10835063
NCBI登录号 :
NP_002511.1
NCBI基因登录号 :
NM_002520.6
UniProt数据库登录号 :
P06748
NCBI分子量 :
28,400 Da
NCBI信号通路 :
Aurora B Signaling Pathway 138080!!BARD1 Signaling Events Pathway 137959!!Cell Cycle Pathway 530733!!Chromosome Maintenance Pathway 161048!!Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway 161050!!Disease Pathway 530764!!HIF-1-alpha Transcription Factor Network Pathway 138045!!HIV Infection Pathway 105983!!Host Interactions Of HIV Factors Pathway 106010!!Interactions Of Rev With Host Cellular Proteins Pathway 106014
NCBI总结 :
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
规格 :
0.05毫克
价格 :
495美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。