抗体

Mouse Monoclonal [clone VG-1] (IgG1) to Human VEGFA / VEGF

MBS245485

0.05毫克

495美元

单克隆

小鼠

未共轭

VG-1

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

Mouse Monoclonal [clone VG-1] (IgG1) to Human VEGFA / VEGF

血管内皮生长因子A/血管内皮生长因子

Anti-VEGFA / VEGF Antibody (clone VG-1) IHC-plus; VEGFA; VPF; Vascular permeability factor; VEGF; VEGF-A; MVCD1; Human VEGFA; VEGF

vascular endothelial growth factor A isoform b; Vascular endothelial growth factor A; vascular endothelial growth factor A; vascular permeability factor; vascular endothelial growth factor A; Vascular permeability factor; VPF

血管内皮生长因子A

血管内皮生长因子

血管内皮生长因子A;血管内皮生长因子A;VPF;血管内皮生长因子;MVCD1;血管内皮生长因子;血管内皮生长因子-A;VPF

VEGFA_HUMAN

单克隆

IgG1

VG-1

小鼠

人类

395

the 121, 165, and 189 VEGF isoforms of Human origin

蛋白质A/G纯化

PBS, 0.1% 叠氮化钠, 0.2% 明胶。 来源在TCS

0.1毫克/毫升

Store at +4 degree C. DO NOT FREEZE.

免疫组化(免疫组化-石蜡), 免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)

ELISA, IHC-P (1:50), WB (1:200). Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.

Target Species: Human. Immunogen Description: Recombinant VEGF.

Immunogen Type: Recombinant protein. Immunogen: VEGFA / VEGF antibody was raised against recombinant VEGF.

Family: PDGF

VEGFA was originally isolated as a heparin-binding secreted factor from bovine pituitary folliculo-stellate cells. It is a direct acting mitogen specific for vascular endothelial cells and capable of stimulating angiogenesis in vivo. In addition to inducing endothelial cell proliferation it promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Molecular cloning has revealed multiple forms of VEGFA arising from alternative splicing of the RNA transcript.

76781481

NP_003367.4

NM_003376.5

P15692

34,406 Da

Angiogenesis Pathway (198772); Axon Guidance Pathway (105688); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Cellular Response To Hypoxia Pathway (645259); Cellular Responses To Stress Pathway (645258); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Developmental Biology Pathway (477129); EPH-Ephrin Signaling Pathway (1127691)

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]

0.05毫克

495美元