抗体

PPIA多克隆抗体

MBS2518180

0.02毫升

110美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

PPIA多克隆抗体

[PPIA]

[CYPA;CYPH;HEL-S-69p]

[PPIA; Peptidyl-prolyl cis-trans isomerase A; peptidyl-prolyl cis-trans isomerase A; PPIase A; T cell cyclophilin; cyclosporin A-binding protein; epididymis secretory sperm binding protein Li 69p; rotamase A; peptidylprolyl isomerase A (cyclophilin A); Cyclophilin A; Cyclosporin A-binding protein; Rotamase APeptidyl-prolyl cis-trans isomerase A, N-terminally processed]

[PPIA]

[PPIA;PPIA;CYPA;CYPH;HEL-S-69p;CYPA;PPIase A]

PPIA_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

165

亲和纯化

Store at -20 degree C. Avoid freeze / thaw cycles.

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

WB: 1:200-1:1000

免疫印迹(免疫印迹)

Immunogen: Recombinant protein of human PPIA. Calculated Molecular Weight: 18kDa

Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

48145531

BC000689

P62937

APOBEC3G Mediated Resistance To HIV-1 Infection Pathway (106016); Assembly Of The HIV Virion Pathway (106008); Basigin Interactions Pathway (106065); Binding And Entry Of HIV Virion Pathway (105986); Budding And Maturation Of HIV Virion Pathway (106009); Cell Surface Interactions At The Vascular Wall Pathway (106062); Disease Pathway (530764); Early Phase Of HIV Life Cycle Pathway (105985); HIV Infection Pathway (105983); HIV Life Cycle Pathway (105984)

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008]

PPIA: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Interacts with HIV-1 Capsid protein. Binds cyclosporin A (CsA). CsA mediates some of its effects via an inhibitory action on PPIase. Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. Protein type: RNA-binding; EC 5.2.1.8; Isomerase; Cyclophilin. Chromosomal Location of Human Ortholog: 7p13. Cellular Component: extracellular space; focal adhesion; membrane; extracellular region; nucleus; cytosol. Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; unfolded protein binding; virion binding; peptide binding. Biological Process: release of virus from host; platelet activation; uncoating of virus; protein peptidyl-prolyl isomerization; positive regulation of viral genome replication; protein folding; viral reproduction; RNA-dependent DNA replication; virus assembly; viral infectious cycle; platelet degranulation; positive regulation of protein secretion; entry into host cell; blood coagulation; leukocyte migration; regulation of viral genome replication

0.02毫升

110美元

0.06毫升

150

0.12毫升

225

0.2毫升

360