抗体

MMP15多克隆抗体

MBS2520010

0.02毫升

110美元

多克隆

兔

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

MMP15多克隆抗体

[MMP15]

[MTMMP2, SMCP-2, MT2-基质金属蛋白酶]

[matrix metalloproteinase-15 preproprotein; Matrix metalloproteinase-15; matrix metalloproteinase-15; MMP-15; MT-MMP 2; MT2MMP; matrix metalloproteinase 15 (membrane-inserted); membrane-type matrix metalloproteinase 2; membrane-type-2 matrix metalloproteinase; matrix metallopeptidase 15 (membrane-inserted); Membrane-type matrix metalloproteinase 2; MT-MMP 2; MTMMP2; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MT2MMP; SMCP-2]

[MMP15]

[MMP15;MMP15;MTMMP2;SMCP-2;MT2-基质金属蛋白酶;基质金属蛋白酶-15;MT-基质金属蛋白酶2;MTMMP2;MT2-基质金属蛋白酶;MT2MMP]

MMP15_HUMAN

多克隆

IgG

兔

人类, 小鼠

669

亲和纯化

存放在-20°C。 避免反复冷冻/解冻

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

WB: 1:500-1:2000

免疫印迹(免疫印迹)

Immunogen: Recombinant protein of human MMP15. Calculated MW: 76kDa

Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Cancer; Cell biology

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is amember of the membrane-type MMP (MT-MMP) subfamily; eacHuman, Mouseember of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.

4505211

BC006412

NM_002428.2

Activation Of Matrix Metalloproteinases Pathway (576264); Collagen Degradation Pathway (730309); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Matrix Metalloproteinases Pathway (198900)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008]

MMP15: Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. Belongs to the peptidase M10A family. Protein type: Protease; Membrane protein, integral; EC 3.4.24.-. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: extracellular matrix; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; zinc ion binding; metalloendopeptidase activity; enzyme activator activity; calcium ion binding. Biological Process: positive regulation of catalytic activity; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; protein modification process; proteolysis; response to estradiol stimulus

0.02毫升

110美元

0.06毫升

150

0.12毫升

225

0.2毫升

360