产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
MAGEA3多克隆抗体
目录 :
MBS2527540
规格 :
0.02毫升
价格 :
110美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS2527540 图像 1
Western Blot analysis of Human testis tissue, A549 and PC3 cell using MAGEA3 Polyclonal Antibody at dilution of 1:400
图像 2 :
MyBioSource MBS2527540 图像 2
Immunohistochemistry of paraffin-embedded Human tonsil using MAGEA3 Polyclonal Antibody at dilution of 1:50
图像 3 :
MyBioSource MBS2527540 图像 3
Immunohistochemistry of paraffin-embedded Human liver cancer using MAGEA3 Polyclonal Antibody at dilution of 1:50
产品信息
目录号 :
MBS2527540
产品类型 :
抗体
产品全称 :
MAGEA3多克隆抗体
产品简称 :
[MAGEA3]
产品名称同义词 :
[HIP8;HYPD;CT1.3;MAGE3;MAGEA6]
其他名称 :
[melanoma-associated antigen 3; Melanoma-associated antigen 3; melanoma-associated antigen 3; MAGE-3 antigen; antigen MZ2-D; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3; melanoma antigen family A, 3; melanoma antigen family A3; Antigen MZ2-D; Cancer/testis antigen 1.3; CT1.3; MAGE-3 antigen]
产品基因名称 :
[MAGEA3]
其他基因名称 :
[MAGEA3;MAGEA3;HIP8;HYPD;CT1.3;MAGE3;MAGEA6;MAGE3;CT1.3]
UniProt数据库进入名 :
MAGA3_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
序列长度 :
314
纯度 :
亲和纯化
储存稳定性 :
Store at -20 degree C (regular). Avoid freeze / thaw cycles.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
WB: 1:500-1:2000。 IHC: 1:50-1:200
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫组化(免疫组化)
image3头 :
免疫组化(免疫组化)
其它信息1 :
Immunogen: Synthetic peptide of human MAGEA3
其他信息2 :
Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. Note: Centrifuge before opening to ensure complete recovery of vial contents.
产品种类 :
Epigenetics
产品描述 :
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
NCBI GI登录号 :
4885467
NCBI登录号 :
NP_005353.1
NCBI基因登录号 :
NM_005362.3
UniProt数据库登录号 :
P43357
NCBI分子量 :
35kDa
NCBI总结 :
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
MAGEA3: Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Protein type: Cancer Testis Antigen (CTA). Chromosomal Location of Human Ortholog: Xq28. Molecular Function: protein binding
尺寸1 :
0.02毫升
价格1 :
110美元
尺寸2 :
0.06毫升
价格2 :
150
size3 :
0.12毫升
价格3 :
225
size4 :
0.2毫升
price4 :
360
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。