产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
IL17A单克隆抗体
目录 :
MBS2542255
规格 :
0.06毫升
价格 :
220美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
[4679]
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 酶免疫法
更多信息或购买 :
图像
图像 1 :
Western Blot analysis of U-937 cells using IL-17 Monoclonal Antibody at dilution of 1:500
产品信息
目录号 :
MBS2542255
产品类型 :
抗体
产品全称 :
IL17A单克隆抗体
产品简称 :
[IL17A]
产品名称同义词 :
[CTLA 8; CTLA-8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL 17A; IL-17; IL-17A; IL17; IL17; Il17a; Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); Interleukin 17A; Interleukin-17A; Interleukin17; Interleukin17A; OTTHUMP00000016597; OTTMUSP00000046003]
其他名称 :
[白细胞介素17A;白细胞介素17A;白细胞介素17A;白细胞介素17A;细胞毒性T淋巴细胞
抗原8;CTLA-8]
产品基因名称 :
[IL17A]
产品基因名称同义词 :
[IL-17]
其他基因名称 :
[IL17A;IL17A;白细胞介素-17;CTLA8;IL-17;CTLA-8;IL-17A;CTLA8;白细胞介素-17;IL-17;IL-17A;CTLA-8]
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
[4679]
宿主 :
小鼠
反应物种 :
人类
序列长度 :
155
纯度 :
蛋白质G纯化
形式 :
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
储存稳定性 :
存放在-20°C。 避免反复冷冻/解冻
检测过的应用 :
免疫印迹(免疫印迹), 酶联免疫吸附测定(EIA)
应用笔记 :
WB: 1:200-1:2000
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: Fusion protein of IL-17. Calculated MW: 15aa, 18kDa. Observed MW: 18kDa
其他信息2 :
Conjugation: Unconjugated
产品种类 :
Cancer; Immunology
产品描述 :
IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.
NCBI GI登录号 :
4504651
NCBI登录号 :
NP_002181.1
NCBI基因登录号 :
NM_002190.2
UniProt数据库登录号 :
Q16552
NCBI信号通路 :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL23-mediated Signaling Events Pathway (138000); IL27-mediated Signaling Events Pathway (137929); Inflammatory Bowel Disease Pathway (842771); Rheumatoid Arthritis Pathway (200309); Rheumatoid Arthritis Pathway (200269); TCR Signaling Pathway (198862)
NCBI总结 :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
尺寸1 :
0.06毫升
价格1 :
220美元
尺寸2 :
0.12毫升
价格2 :
290
size3 :
0.2毫升
价格3 :
435
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。