产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
纯化抗小鼠CD49b单克隆抗体
目录 :
MBS2553981
规格 :
0.05毫克
价格 :
100美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
[DX5]
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪, 流式细胞仪
更多信息或购买 :
产品信息
目录号 :
MBS2553981
产品类型 :
抗体
产品全称 :
纯化抗小鼠CD49b单克隆抗体
产品简称 :
[CD49b]
产品名称同义词 :
[Mouse CD49b; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b]
其他名称 :
[Integrin alpha-2; integrin alpha-2; integrin alpha 2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD_antigen: CD49b]
产品基因名称 :
[CD49b]
其他基因名称 :
[Itga2;Itga2;DX5;血小板表面胶原蛋白受体;CD49B;血小板表面胶原蛋白受体]
克隆性 :
单克隆
抗体亚型 :
IgM
克隆 :
[DX5]
宿主 :
大鼠
反应物种 :
小鼠
序列长度 :
1,178
形式 :
Liquid; PBS with 0.05% Proclin300
储存稳定性 :
Shipping: Ships at 4 degree C. Stability & Storage: Store at 2-8 degree C and protected from prolonged to light. Do not freeze.
检测过的应用 :
流式细胞仪(FC/流式细胞仪), 免疫组化(免疫组化)
应用笔记 :
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <=0.25 ug per million cells in 100 ul volume.
其它信息1 :
Conjugation: Unconjugated
其他信息2 :
Cellular Localization: Membrane
产品描述 :
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin alpha chain also known as alpha2 integrin, VLA-2 alpha chain, and integrin alpha2 chain. CD49b non-covalently associates with CD29 (beta1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
产品引用 :
1. Arase H, et al. 2001. J. Immunol. 167:1141. 2. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 3. Sasaki K, et al. 2003. Int. Immunol. 15:701. 4. Inoue O, et al. 2003. J. Cell Biol. 160:769.
NCBI登录号 :
NP_032422.2
UniProt数据库登录号 :
Q62469
NCBI分子量 :
128,955 Da
UniProt数据库总结 :
Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis.
尺寸1 :
0.05毫克
价格1 :
100美元
尺寸2 :
0.1毫克
价格2 :
115
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。