产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
山羊甲状腺素(T3)酶联免疫吸附试剂盒
目录 :
MBS265631
规格 :
48-Strip-Wells
价格 :
315美元
更多信息或购买 :
产品信息
目录号 :
MBS265631
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
山羊甲状腺素(T3)酶联免疫吸附试剂盒
产品简称 :
甲状腺素(T3)
其他名称 :
thyroid hormone receptor alpha isoform 2; Thyroid hormone receptor alpha; thyroid hormone receptor alpha; EAR-7; c-erbA-alpha; ERBA-related 7; V-erbA-related protein 7; triiodothyronine receptor; nuclear receptor subfamily 1 group A member 1; thyroid normone nuclear receptor alpha variant 1; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); thyroid hormone receptor, alpha; Nuclear receptor subfamily 1 group A member 1; V-erbA-related protein 7; EAR-7; c-erbA-1; c-erbA-alpha
产品基因名称 :
T3
其他基因名称 :
THRA;THRA;AR7;EAR7;ERBA;CHNG6;ERBA1;NR1A1;THRA1;THRA2;ERB-T;c-ERBA;EAR7;ERBA1;NR1A1;THRA1;THRA2;耳-7
UniProt数据库进入名 :
THA_HUMAN
反应物种 :
山羊
序列长度 :
490
特异性 :
No cross-reaction with other factors.
储存稳定性 :
Store all reagents at 2-8 degree C.
其它信息1 :
Samples: Goat serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant T3 concentration. Assay Type: Sandwich. Detection Range: 20 nmol/L-0.312 nmol/L. Sensitivity: 0.06 nmol/L.
其他信息2 :
Intra-assay Precision: ? 8%. Inter-assay Precision: ? 12%
产品描述 :
Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Goat T3 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
NCBI GI登录号 :
300116309
NCBI登录号 :
NP_001177848.1
NCBI基因登录号 :
NM_001190919.1
NCBI分子量 :
50,465 Da
NCBI信号通路 :
Endochondral Ossification Pathway (198812); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Receptor Transcription Pathway (105979); Nuclear Receptors Pathway (198848); Thyroid Hormone Signaling Pathway (946598)
NCBI总结 :
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
TR-alpha: nuclear hormone receptor and transcription factor. High affinity receptor for triiodothyronine. Interacts with SRC-3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Four splice variant isoforms have been described. Protein type: DNA-binding; Transcription factor; Nuclear receptor. Chromosomal Location of Human Ortholog: 17q11.2. Cellular Component: nucleoplasm; cytosol; nucleus. Molecular Function: protein domain specific binding; protein binding; zinc ion binding; TATA-binding protein binding; chromatin DNA binding; sequence-specific DNA binding; protein complex binding; steroid hormone receptor activity; thyroid hormone receptor activity; transcription factor binding; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcriptional preinitiation complex assembly; transcription initiation from RNA polymerase II promoter; ossification; cytoplasmic sequestering of transcription factor; intracellular receptor-mediated signaling pathway; hormone-mediated signaling; positive regulation of female receptivity; regulation of myeloid cell apoptosis; regulation of lipid catabolic process; regulation of heart contraction; regulation of transcription from RNA polymerase II promoter; learning and/or memory; female courtship behavior; thyroid gland development; erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; gene expression; response to cold; negative regulation of transcription, DNA-dependent; cartilage condensation. Disease: Hypothyroidism, Congenital, Nongoitrous, 6
尺寸1 :
48-Strip-Wells
价格1 :
315美元
尺寸2 :
96-Strip-Wells
价格2 :
490
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。