产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
Human Acidic Fibroblast Growth Factor (aFGF) ELISA Kit
目录 :
MBS266169
规格 :
48-Strip-Wells
价格 :
250美元
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS266169 图像 1
产品信息
目录号 :
MBS266169
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
Human Acidic Fibroblast Growth Factor (aFGF) ELISA Kit
产品简称 :
[Acidic Fibroblast Growth Factor (aFGF)]
其他名称 :
[acidic fibroblast growth factor, partial; Fibroblast growth factor 1; fibroblast growth factor 1; heparin-binding growth factor 1; beta-endothelial cell growth factor; endothelial cell growth factor, beta; endothelial cell growth factor, alpha; fibroblast growth factor 1 (acidic); Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1]
产品基因名称 :
[aFGF]
其他基因名称 :
[成纤维细胞生长因子-1;成纤维细胞生长因子-1;AFGF;ECGF;FGFA;ECGFA;ECGFB;FGF-1;HBGF1;HBGF-1;GLIO703;ECGF乙;FGF甲;FGFA;FGF-1;aFGF;ECGF;HBGF-1]
UniProt数据库进入名 :
FGF1_HUMAN
反应物种 :
人类
序列长度 :
59
特异性 :
No cross-reaction with other factors.
储存稳定性 :
Store all reagents at 2-8 degree C.
image1头 :
Typical Testing Data/Standard Curve (for reference only)
其它信息1 :
Samples: human serum, plasma or cell culture supernatant. Detection Range: 1000 pg/ml-15.6 pg/ml. Sensitivity: 5 pg/mL
其他信息2 :
Intra-assay Precision: ? 8%. Inter-assay Precision: ? 12%
产品描述 :
Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human aFGF monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
NCBI GI登录号 :
456828
NCBI登录号 :
AAB29059.1
NCBI分子量 :
6,698 Da
NCBI信号通路 :
Activated Point Mutants Of FGFR2 Pathway (645281); Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signal Transduction Pathway (106385); Downstream Signaling Of Activated FGFR Pathway (160957); FGF Signaling Pathway (137989)
NCBI总结 :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
UniProt数据库总结 :
FGF1: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1. Part of a Cu(2+)-dependent multiprotein aggregate containing FGF1, S100A13 and SYT1. Interacts with SYT1. Interacts with S100A13. Belongs to the heparin-binding growth factors family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine; Motility/polarity/chemotaxis; Cell development/differentiation. Chromosomal Location of Human Ortholog: 5q31. Cellular Component: nucleoplasm; proteinaceous extracellular matrix; extracellular space; extracellular region; nucleolus; cell cortex; cytosol. Molecular Function: heparin binding; protein binding; growth factor activity; Hsp70 protein binding; fibroblast growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; anatomical structure morphogenesis; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; multicellular organismal development; positive regulation of cholesterol biosynthetic process; signal transduction; positive regulation of MAP kinase activity; positive regulation of angiogenesis; induction of an organ; positive regulation of cell division; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; positive regulation of epithelial cell proliferation; lung development; positive regulation of cell migration
尺寸1 :
48-Strip-Wells
价格1 :
250美元
尺寸2 :
96-Strip-Wells
价格2 :
365
size3 :
5x96-Strip-Wells
价格3 :
1480
size4 :
10x96-Strip-Wells
price4 :
2620
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。