产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
淋巴细胞型选择素
目录 :
MBS340243
规格 :
1毫升
价格 :
350美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
MBS340243
产品类型 :
抗体
产品全称 :
淋巴细胞型选择素
产品简称 :
淋巴细胞型选择素
产品名称同义词 :
抗-淋巴细胞型选择素
其他名称 :
L-selectin; L-selectin; L-selectin; gp90-MEL; OTTHUMP00000032696; pln homing receptor; lymph node homing receptor; lymphocyte adhesion molecule 1; leukocyte surface antigen Leu-8; CD62 antigen-like family member L; leukocyte-endothelial cell adhesion molecule 1; selectin L; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL
其他基因名称 :
SELL;SELL;TQ1;LAM1;LEU8;LNHR;LSEL;CD62L;LYAM1;PLNHR;LECAM1;LNHR;LYAM1
UniProt数据库进入名 :
LYAM1_HUMAN
克隆性 :
多克隆
宿主 :
序列长度 :
372
形式 :
Ig fraction, liquid
储存稳定性 :
Store at -20 degree C. Avoid repeated freeze/thaw cycles.
其它信息1 :
Immunogen: Recombinant Human L-Selectin
其他信息2 :
Buffer: 20mM Phosphate, 150mM Sodium Chloride, pH 7.2. Preservative: 0.09% Sodium Azide
NCBI GI登录号 :
5852072
NCBI登录号 :
CAB55488.1
UniProt数据库登录号 :
Q9UJ43
NCBI分子量 :
42,187 Da
NCBI信号通路 :
Adaptive Immunity Signaling Pathway 366160!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Hemostasis Pathway 106028!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413
NCBI总结 :
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
UniProt数据库总结 :
Function: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Ref.10. Subunit structure: Interaction with PSGL1/SELPLG and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of PSGL1 and PODXL2, and tyrosine sulfation modifications of PSGL1. Sulfation on Y-51 of PSGL1 is important for L-selectin binding. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Expressed in B cell lines and T lymphocytes. Ref.2. Sequence similarities: Belongs to the selectin/LECAM family.Contains 1 C-type lectin domain.Contains 1 EGF-like domain.Contains 2 Sushi (CCP/SCR) domains. Sequence caution: The sequence CAA34203.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAB43536.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAB43537.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
规格 :
1毫升
价格 :
350美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。