抗体

标签-72

MBS370108

5 + Control Slides

115美元

单克隆

小鼠

未共轭

Tag72-22

人类, 秀丽隐杆线虫

抗体

标签-72

标签-72

Temporarily Assigned Gene name family member (tag-72); mRNA cap guanine-N7 methyltransferase; Temporarily Assigned Gene name family member (tag-72); mRNA (guanine-N(7)-)-methyltransferase

标签-72

标签72;标签72;标签72

MCES_CAEEL

单克隆

IgG1/K

Tag72-22

小鼠

人类

TAG-72 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

Store at 2 to 8 degree C in the dark.

Control: Breast Carcinoma. Localization: Cytoplasmic

Reactivity Note: Paraffin, Frozen

Tumor-associated glycoprotein (TAG-72) has been shown to be expressed in a wide variety of epithelial malignant tissues. TAG-72 antigen is a high molecular glycoprotein found on the surface of many cancer cells, including breast, colon and pancreatic cells. It is present in human Adenocarcinomas and in lesser amounts, non-neoplastic tissues. The majority of human Adenocarcinomas including Colorectal, Pancreatic, Gastric, Ovarian, Endometrial, Mammary, and Non-Small Cell Lung Cancer display some cell populations that are positive for TAG-72. TAG-72 has also been found to be useful for the distinction between Mesothelioma and Adenocarcinoma; however, false positive reactions can occur so results must be interpreted with the utmost caution.

71980935

NP_492674.2

NM_060273.5

Q9XVS1

43181 Da

Formation And Maturation Of MRNA Transcript Pathway (363284); Gene Expression Pathway (363283); RNA Pol II CTD Phosphorylation And Interaction With CE Pathway (363291); RNA Polymerase II Transcription Pathway (363285); Transcription Pathway (363432); MRNA Capping Pathway (363134); MRNA Processing Pathway (363133); MRNA Processing Pathway (198995); MRNA Surveillance Pathway (193196); MRNA Surveillance Pathway (193184)

Function: mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC. Catalytic activity: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. Subcellular location: Nucleus. Sequence similarities: Belongs to the methyltransferase superfamily. mRNA cap methyltransferase family.

5 + Control Slides

115美元

3 ml (Prediluted)

135

7 ml (Prediluted)

150

0.1 mL (Concentrate)

170

15 ml (Prediluted)

215