抗APLP2抗体 | MyBioSource MBS416063 产品信息

产品简要

公司名称 :

MyBioSource

产品类型 :

抗体

产品名称 :

抗APLP2抗体

MBS416063

规格 :

0.1毫升

价格 :

230美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

未共轭

应用 :

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

更多信息或购买 :

MyBioSource 产品网页

产品信息

目录号 :

MBS416063

产品类型 :

抗体

产品全称 :

抗APLP2抗体

产品简称 :

APLP2

产品基因名称 :

APLP2

克隆性 :

多克隆

宿主 :

兔

反应物种 :

人类, 小鼠, 大鼠

特异性 :

Human and predicted against mouse and rat

纯度 :

亲和纯化

形式 :

液体

浓度 :

100微克/100微升

储存稳定性 :

This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

检测过的应用 :

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)

应用笔记 :

ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:1,000-1:2,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.

其它信息1 :

Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide

其他信息2 :

Immunogen: Rabbit polyclonal APLP2 (1) antibody was raised against a recombinate human APLP2 protein 262-491aa (BC000373).

产品描述 :

This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

产品引用 :

(1) Peters,H.L., Tuli,A., Sharma,M. et al. Regulation of major histocompatibility complex class I molecule expression on cancer cells by amyloid precursor-like protein 2. Immunol. Res. 51 (1), 39-44 (2011).

尺寸1 :

0.1毫升

价格1 :

230美元

更多信息或购买 :

MyBioSource 产品网页

公司信息