抗体

抗TGFB2抗体

MBS416658

0.1毫升

230美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠, 斑马鱼

酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

抗TGFB2抗体

[TGFB2]

[transforming growth factor beta-2; transforming growth factor beta-2; tgf beta 2; transforming growth factor, beta 2]

[TGFB2]

[tgfb2]

多克隆

IgG

兔

Human, Mouse, Rat. Not yet tested in other species.

411

亲和纯化

液体

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

酶联免疫吸附测定(EIA), 免疫组化(免疫组化)

Peptide ELISA titer: 1:1,000-1:10,000. Immunohistochemistry: 1:100-500. Optimal dilutions/concentrations should be determined by the end user

免疫组化(免疫组化)

Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide

Immunogen: Rabbit polyclonal TGFB2 antibody was raised against a peptide from N terminal residues of human TGFB2 protein.

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

(1) Schierano,G., Pejrone,G., Brusco,P., et al.TNF-alpha TGF-beta2 and IL-1beta levels in gingival and peri-implant crevicular fluid before and after de novo plaque accumulation. J. Clin. Periodontol. 35 (6), 532-538 (2008)

35902884

NP_919366.1

NM_194385.1

Cell Cycle Pathway (83631); Cell Cycle Pathway (463); Cytokine-cytokine Receptor Interaction Pathway (119260); Cytokine-cytokine Receptor Interaction Pathway (460); ECM Proteoglycans Pathway (1114001); ERK1 - ERK2 MAPK Cascade Pathway (198962); Elastic Fibre Formation Pathway (1113996); Endochondral Ossification Pathway (921002); Endocytosis Pathway (102262); Endocytosis Pathway (102181)

0.1毫升

230美元