产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗cox2抗体
目录 :
MBS416804
规格 :
0.1毫升
价格 :
230美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS416804 图像 1
产品信息
目录号 :
MBS416804
产品类型 :
抗体
产品全称 :
抗cox2抗体
产品简称 :
[cox2]
其他名称 :
[Mus musculus prostaglandin-endoperoxide synthase 2 (Ptgs2), mRNA; Prostaglandin G/H synthase 2; prostaglandin G/H synthase 2; PES-2; PGH synthase 2; PHS II; cyclooxygenase 2; cyclooxygenase-2; glucocorticoid-regulated inflammatory cyclooxygenase; gripghs; macrophage activation-associated marker protein P71/73; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; Cyclooxygenase-2; COX-2; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; Macrophage activation-associated marker protein P71/73; PES-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2; TIS10 protein]
产品基因名称 :
[cox2]
其他基因名称 :
[Ptgs2; Ptgs2; COX2; Cox-2; PHS-2; Pghs2; TIS10; PGHS-2]
UniProt数据库进入名 :
PGH2_MOUSE
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
Human, Mouse, Rat. Not yet tested on other species
序列长度 :
4150
纯度 :
纯化
形式 :
液体
浓度 :
100微克/100微升
储存稳定性 :
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
检测过的应用 :
酶联免疫吸附测定, 免疫印迹(免疫印迹)
应用笔记 :
Peptide ELISA titer: 1:10,000-1:40,000. Western blot analysis: 1:200-500. Optimal dilutions/concentrations should be determined by the end user
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Antibody Type: Primary Antibody. Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
其他信息2 :
Immunogen: Synthetic peptide conjugated to KLH
产品引用 :
(1) Yang,H., Zhang,J., Andreasson,K. and Chen,C. COX-2 oxidative metabolism of endocannabinoids augments hippocampal synaptic plasticity. Mol. Cell. Neurosci. 37 (4), 682-695 (2008).
NCBI GI登录号 :
118130137
NCBI登录号 :
NP_035328.2
NCBI基因登录号 :
NM_011198
NCBI分子量 :
69,013 Da
NCBI信号通路 :
Arachidonic Acid Metabolism Pathway (83190); Arachidonic Acid Metabolism Pathway (1110914); Arachidonic Acid Metabolism Pathway (366); Arachidonic Acid Metabolism Pathway (522975); Arachidonic Acid Metabolism Via COX (Cyclooxygenase) Pathway (522976); Chemical Carcinogenesis Pathway (673229); Chemical Carcinogenesis Pathway (673237); Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (1111378); Defective BTD Causes Biotidinase Deficiency Pathway (1111393); Defective CD320 Causes Methylmalonic Aciduria Pathway (1111390)
UniProt数据库总结 :
COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family. Protein type: Lipid Metabolism - arachidonic acid; EC 1.14.99.1; Oxidoreductase. Cellular Component: neuron projection; protein complex; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; caveola; nucleus. Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; prostaglandin-endoperoxide synthase activity; peroxidase activity; protein homodimerization activity; enzyme binding; dioxygenase activity; metal ion binding; heme binding; oxidoreductase activity; lipid binding. Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of NF-kappaB import into nucleus; response to lipopolysaccharide; decidualization; sensory perception of pain; prostaglandin biosynthetic process; fatty acid metabolic process; positive regulation of synaptic transmission, glutamatergic; negative regulation of synaptic transmission, dopaminergic; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; regulation of blood pressure; negative regulation of smooth muscle contraction; positive regulation of cell proliferation; angiogenesis; positive regulation of smooth muscle contraction; inflammatory response; fatty acid biosynthetic process; negative regulation of calcium ion transport; cyclooxygenase pathway; positive regulation of synaptic plasticity; learning; memory; prostaglandin metabolic process; regulation of cell proliferation; ovulation; keratinocyte differentiation; response to cytokine stimulus; brown fat cell differentiation; positive regulation of vasoconstriction; positive regulation of fever; lipid metabolic process; response to oxidative stress; anagen; embryo implantation
尺寸1 :
0.1毫升
价格1 :
230美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。