抗体

山羊抗Ku80/XRCC5抗体

MBS420912

0.1毫克

290美元

多克隆

山羊

未共轭

免疫印迹, 酶免疫法

抗体

山羊抗Ku80/XRCC5抗体

Ku80/XRCC5

XRCC5; KU80; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining Ku autoantigen; 80kDa); HGNC:12833; KARP-1; KARP1; Ku86; NFIV; ATP-dependent DNA helicase II; DNA repair protein XRCC5; Ku86 autoantigen related protein 1; Ku autoantigen; 80kD; X-ray repair; complementing defective; repair in Chinese hamster; XRCC5; KU80; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining Ku autoantigen, 80kDa); HGNC:12833; KARP-1; KARP1; Ku86; NFIV; ATP-dependent DNA helicase II; DNA repair protein XRCC5; Ku86 autoantigen related protein 1; Ku autoantigen, 80kD; X-ray repair, complementing defective, repair in Chinese hamster

X-ray repair cross-complementing protein 5; X-ray repair cross-complementing protein 5; X-ray repair cross-complementing protein 5; TLAA; CTC85; CTCBF; nuclear factor IV; Ku autoantigen, 80kDa; DNA repair protein XRCC5; thyroid-lupus autoantigen; 86 kDa subunit of Ku antigen; lupus Ku autoantigen protein p86; Ku86 autoantigen related protein 1; CTC box-binding factor 85 kDa subunit; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

XRCC5

XRCC5;XRCC5;KU80;KUB2;Ku86;NFIV;KARP1;KARP-1;G22P2;CTC85;CTCBF;TLAA

XRCC5_HUMAN

多克隆

山羊

人类

732

SLAKKDEKTDTLED

通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

肽酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

Western Blot: Approx 80-85kDa band observed in lysates of HeLa (calculated MW of 82.7kDa according to NP_066964.1). Recommended concentration: 0.1-0.3ug/ml. An additional band of 75kDa was observed consistent with products from other sources. Peptide ELISA: antibody detection limit dilution 1:16000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-SLAKKDEKTDTLED, from the internal region of the protein sequence according to NP_066964.1.

Corresponding Immunizing Peptide: Catalog #MBS425330

10863945

NP_066964.1

NM_021141.3

82,705 Da

2-LTR Circle Formation Pathway 105993!!BARD1 Signaling Events Pathway 137959!!Coregulation Of Androgen Receptor Activity Pathway 138085!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!DNA Repair Pathway 105837!!DNA-PK Complex Pathway 413430!!DNA-PK Complex Pathway 890556!!Disease Pathway 530764!!Double-Strand Break Repair Pathway 105861!!Early Phase Of HIV Life Cycle Pathway 105985

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

0.1毫克

290美元