抗体

山羊抗平滑肌阿尔法肌动蛋白抗体

MBS421038

0.1毫克

300美元

多克隆

山羊

未共轭

人类, 小鼠, 大鼠, 狗

免疫印迹, 免疫组化, 免疫细胞化学, 酶免疫法

抗体

山羊抗平滑肌阿尔法肌动蛋白抗体

平滑肌阿尔法肌动蛋白

ACTA2; actin, alpha 2, smooth muscle, aorta; OTTHUMP00000020042; ACTSA; AAT6; ACTSA; alpha 2 actin; alpha-cardiac actin; growth-inhibiting gene 46; smooth muscle alpha-actin; actin; alpha 2; smooth muscle; aorta antibody; OTTHUMP00000020042 antibody; ACTA2 antibody; ACTSA antibody; AAT6 antibody; ACTSA antibody; alpha 2 actin antibody; alpha-cardiac actin antibody; growth-inhibiting gene 4 antibody; smooth muscle alpha-actin antibody; Smooth muscle alpha-actin; Smooth muscle alpha-actin

actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein

大动脉平滑肌肌动蛋白alpha2

大动脉平滑肌肌动蛋白alpha2;大动脉平滑肌肌动蛋白alpha2;AAT6;ACTSA;MYMY5;ACTSA;ACTVS

ACTA_HUMAN

多克隆

山羊

Tested: Human, Mouse, Rat, Pig; Expected from sequence similarity: Human, Mouse, Rat, Dog

377

EEEDSTALVC

通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

肽酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫荧光(IF), 免疫组化(免疫组化)

Peptide ELISA: Antibody detection limit dilution 1: 2000. Immunohistochemistry: In paraffin embedded Human and Murine Lung shows staining of the alveolar walls. Recommended concentration, 2-4ug/ml. Data obtained from a different batch (different goat). Western Blot: Approx 40-45kDa band observed in Human Duodenum, Heart and Skeletal Muscle lysates (calculated MW of 42. 0kDa according to NP_001604.1). Recommended concentration: 0.3-1ug/ml.

Immunogen: Peptide with sequence EEEDSTALVC, from the N Terminus of the protein sequence according to NP_001604.1; NP_001135417.1. Epitope: N Terminus

Note: Variants NP_001604.1 and NP_001135417.1 encode the same protein.

4501883

NP_001604.1

NM_001613.2

42,009 Da

Muscle Contraction Pathway (1269868); Myometrial Relaxation And Contraction Pathways (198759); Smooth Muscle Contraction Pathway (1269870); Striated Muscle Contraction Pathway (198903); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family. Protein type: Cytoskeletal; Contractile; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q23.3. Cellular Component: actin cytoskeleton; cytoplasm; cytosol; extracellular space; filopodium; lamellipodium; protein complex; smooth muscle contractile fiber. Molecular Function: ATP binding; protein kinase binding. Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction. Disease: Aortic Aneurysm, Familial Thoracic 6; Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome

0.1毫克

300美元