产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
山羊抗INDO/IDO抗体
目录 :
MBS421061
规格 :
0.1毫克
价格 :
290美元
克隆性 :
多克隆
宿主 :
山羊
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS421061
产品类型 :
抗体
产品全称 :
山羊抗INDO/IDO抗体
产品简称 :
INDO/IDO
产品名称同义词 :
INDO; indoleamine-pyrrole 2; 3 dioxygenase; HGNC:6059; CD107B; IDO; Indoleamine 2; 3-dioxygenase; indole 2; 3-dioxygenase; IDO1; IDO1; INDO; indoleamine-pyrrole 2,3 dioxygenase; HGNC:6059; CD107B; IDO; Indoleamine 2,3-dioxygenase; indole 2,3-dioxygenase
其他名称 :
indoleamine 2,3-dioxygenase 1; Indoleamine 2,3-dioxygenase 1; indoleamine 2,3-dioxygenase 1; indole 2,3-dioxygenase; indolamine 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase; indoleamine 2,3-dioxygenase 1; Indoleamine-pyrrole 2,3-dioxygenase
产品基因名称 :
IDO1
其他基因名称 :
IDO1;IDO1;IDO;INDO;IDO-1;IDO;INDO;IDO-1
UniProt数据库进入名 :
I23O1_HUMAN
克隆性 :
多克隆
宿主 :
山羊
反应物种 :
人类, 小鼠, 大鼠, 狗
序列长度 :
403
序列 :
CVLANWKKKDPNK
纯度 :
通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的
形式 :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
浓度 :
100ug specific antibody in 200ul
储存稳定性 :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
检测过的应用 :
肽酶联免疫吸附测定(EIA), 免疫组化(免疫组化), 免疫印迹(免疫印迹)
应用笔记 :
Immunohistochemistry: In paraffin embedded Human Colon shows textured staining in the cytoplasm of absorptive cells. Recommended concentration, 4-6ug/ml. Western Blot: Preliminary experiments gave bands at approx 28kDa and 25kDa in lysates of Human Spleen and Tonsil and in Mouse Brain lysate after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 45.3kDa according to NP_002155.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). Peptide ELISA: antibody detection limit dilution 1:8000.
其它信息1 :
Epitope: Internal Region. Immunogen: Peptide with sequence CVLANWKKKDPNK, from the internal region of the protein sequence according to NP_002155.1.
其他信息2 :
Corresponding Immunizing Peptide: Catalog #MBS425254
NCBI GI登录号 :
4504577
NCBI登录号 :
NP_002155.1
NCBI基因登录号 :
NM_002164.5
NCBI分子量 :
45,326 Da
NCBI信号通路 :
African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!NAD Biosynthesis II (from Tryptophan) Pathway 138368!!Tryptophan Catabolism Pathway 106190!!Tryptophan Metabolism Pathway 82964!!Tryptophan Metabolism Pathway 198850!!Tryptophan Metabolism Pathway 332
NCBI总结 :
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
规格 :
0.1毫克
价格 :
290美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。