抗体

山羊抗GRB2抗体

MBS421084

0.1毫克

290美元

多克隆

山羊

未共轭

人类, 小鼠, 大鼠, 狗, 牛

免疫印迹, 免疫组化, 酶免疫法

抗体

山羊抗GRB2抗体

GRB2

GRB2; growth factor receptor-bound protein 2; ASH; ASH protein; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; HT027; abundant SRC homology; epidermal growth factor receptor-binding protein GRB2; growth factor receptor-bound protein 3; NCKAP2; OTTHUMP00000166096; OTTHUMP00000166097; OTTHUMP00000166098; abundant SRC homology; GRB2; growth factor receptor-bound protein 2; ASH; ASH protein; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; HT027; abundant SRC homology; epidermal growth factor receptor-binding protein GRB2; growth factor receptor-bound protein 3; NCKAP2; OTTHUMP00000166096; OTTHUMP00000166097; OTTHUMP00000166098; abundant SRC homology

growth factor receptor-bound protein 2 isoform 1; Growth factor receptor-bound protein 2; growth factor receptor-bound protein 2; HT027; protein Ash; SH2/SH3 adapter GRB2; abundant SRC homology; growth factor receptor-bound protein 3; epidermal growth factor receptor-binding protein GRB2; growth factor receptor-bound protein 2; Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2

GRB2

GRB2;GRB2;ASH;Grb3-3;MST084;NCKAP2;MSTP084;EGFRBP-GRB2;ASH

GRB2_HUMAN

多克隆

山羊

人类, 小鼠, 大鼠, 狗, 牛

217

PRNYVTPVNRNV

通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

肽酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)

Immunohistochemistry: In paraffin embedded Human Tonsil, stains mantle zone and to a lessser extent germinal centre. Data obtained by previous batch (different goat). Recommended concentration, 0.1-0.3ug/ml. Also islets of Langerhans in paraffin embedded Human Pancreas is specifically stained (please contact technical support for details). Western Blot: Approx 26kDa band observed in lysate in cell MOLT4, Human Thymus and Mouse and Rat Brain and Spleen lysates (calculated MW of 25.2kDa according to Human NP_002077.1 and according to Rat NP_110473.2). Recommended for use at 0.05-0.15ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-PRNYVTPVNRNV, from the C Terminus of the protein sequence according to NP_002077.1; NP_987102.1. Corresponding Immunizing Peptide: Catalog #MBS426749

Important Note: This antibody is expected to recognize both reported isoforms (NP_002077.1and NP_987102.1).

4504111

NP_002077.1

NM_002086.4

20,557 Da

Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adaptive Immune System Pathway 366160!!Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway 576249!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 198909

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

0.1毫克

290美元