抗体

山羊抗TRPC6抗体

MBS421378

0.1毫克

290美元

多克隆

山羊

未共轭

人类, 狗, 牛

免疫印迹, 流式细胞仪, 流式细胞仪, 酶免疫法

抗体

山羊抗TRPC6抗体

TRPC6

TRPC6; transient receptor potential cation channel; subfamily C; member 6; HGNC:12338; TRP6; transient receptor potential channel 6; FLJ11098; FLJ14863; FSGS2; TRP6; Goat Anti-TRPC6 (C-term); TRPC6; transient receptor potential cation channel, subfamily C, member 6; HGNC:12338; TRP6; transient receptor potential channel 6; FLJ11098; FLJ14863; FSGS2; TRP6

short transient receptor potential channel 6; Short transient receptor potential channel 6; short transient receptor potential channel 6; TRP-6; transient receptor protein 6; focal segmental glomerulosclerosis 2; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; TRP-6

TRPC6

TRPC6;TRPC6;TRP6;FSGS2;TRP6;TrpC6;TRP-6

TRPC6_HUMAN

多克隆

山羊

人类, 狗, 猪, 牛

931

EKLSMEPNQEETN

通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

肽酶联免疫吸附测定(EIA), 流式细胞仪(FC/流式细胞仪), 免疫印迹(免疫印迹)

Western Blot: Preliminary experiments gave an approx 80kDa band in Human Spleen and Testis lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 106kDa according to NP_004612.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:2000. Flow cytometry: This antibody has been proven to specifically react to TRPC6 in FC.

Epitope: C Terminus. Immunogen: Peptide with sequence C-EKLSMEPNQEETN, from the C Terminus of the protein sequence according to NP_004612.2.

Corresponding Immunizing Peptide: Catalog #MBS428146

5730102

NP_004612.2

NM_004621.5

100,106 Da

Axon Guidance Pathway 105688!!Developmental Biology Pathway 477129!!EPO Signaling Pathway 138051!!Effects Of PIP2 Hydrolysis Pathway 106044!!Elevation Of Cytosolic Ca2+ Levels Pathway 106047!!Endothelins Pathway 137958!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Hemostasis Pathway 106028

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]

0.1毫克

290美元