产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
山羊抗GCH1抗体
目录 :
MBS421787
规格 :
0.1毫克
价格 :
300美元
克隆性 :
多克隆
宿主 :
山羊
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS421787
产品类型 :
抗体
产品全称 :
山羊抗GCH1抗体
产品简称 :
GCH1
产品名称同义词 :
GCH1; GTP cyclohydrolase 1 (dopa-responsive dystonia); DYT5; GCH; GTP-CH-1; GTPCH1; GTP cyclohydrolase 1; guanosine 5'-triphosphate cyclohydrolase I; GCH1 antibody; GTP cyclohydrolase 1 (dopa-responsive dystonia) antibody; DYT5 antibody; GCH antibody; GTP-CH-1 antibody; GTPCH1 antibody; GTP cyclohydrolase 1 antibody; guanosine 5 1-triphosphate cyclohydrolase I antibody
其他名称 :
GTP cyclohydrolase 1 isoform 1; GTP cyclohydrolase 1; GTP cyclohydrolase 1; GTP cyclohydrolase 1; GTP cyclohydrolase I; GTP-CH-I
产品基因名称 :
GCH1
其他基因名称 :
GCH1;GCH1;GCH;DYT5;DYT14;DYT5a;GTPCH1;HPABH4B;GTP-CH-1;DYT5;GCH;GTP-CH-I
UniProt数据库进入名 :
GCH1_HUMAN
克隆性 :
多克隆
宿主 :
山羊
反应物种 :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
序列长度 :
250
序列 :
GKVHIGYLPNKQ
纯度 :
通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的
形式 :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
浓度 :
100ug specific antibody in 200ul
储存稳定性 :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
检测过的应用 :
肽酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
应用笔记 :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx.37kDa band observed in Human Tonsil, Lymph Node and Thymus lysates. Customer's experiments gave identical results in lysates of cell line HUVEC with antibodies raised against different parts of the same protein. (calculated MW of 27.9kDa according to NP_000152.1). Recommended concentration: 0.5-1.5ug/ml.
其它信息1 :
Immunogen: Peptide with sequence C-GKVHIGYLPNKQ, from the internal region of the protein sequence according to NP_000152.1 ; NP_001019195.1 ; NP_001019241.1 ; NP_001019242.1. Epitope: Internal region
其他信息2 :
Note: This antibody is expected to recognize all four isoforms (NP_000152.1 ; NP_001019195.1 ; NP_001019241.1 ; NP_001019242.1)
NCBI GI登录号 :
4503949
NCBI登录号 :
NP_000152.1
NCBI基因登录号 :
NM_000161.2
NCBI分子量 :
25,775 Da
NCBI信号通路 :
Folate Biosynthesis Pathway (83018); Folate Biosynthesis Pathway (404); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Nitric Oxide Pathway (1270115); Tetrahydrobiopterin (BH4) Synthesis, Recycling, Salvage And Regulation Pathway (1270120); ENOS Activation And Regulation Pathway (1270116); Tetrahydrobiopterin Biosynthesis I Pathway (138454); Tetrahydrobiopterin Biosynthesis II Pathway (138455); Tetrahydrobiopterin De Novo Biosynthesis Pathway (142229)
NCBI总结 :
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008]
尺寸1 :
0.1毫克
价格1 :
300美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。